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| Status |
Public on Jun 09, 2023 |
| Title |
Mouse model of Heptablastoma |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Lack of relevant animal models and cell lines hampers the understanding of hepatoblastoma and identification of therapeutic targets. We report a hepatoblastoma murine model that faithfully recapitulates the pathological features of mixed fetal and embryonic hepatoblastoma, with transcriptomics resembling the high-risk gene signatures of human disease
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| Overall design |
Tumor was analyzed from Hepatocellular model at single cell RNA sequencing. The ScRNAseq was performed using 10X genomics -Single cell gene expression kit.
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| Contributor(s) |
Fang J, Singh S, Natarajan S, Yang J, Chen X |
| Citation(s) |
37414763 |
| |
| Submission date |
Jan 20, 2022 |
| Last update date |
Sep 08, 2023 |
| Contact name |
Jun Yang |
| Organization name |
St.Jude Children's Research Hospital
|
| Department |
Surgery
|
| Street address |
262 Danny Thomas Place
|
| City |
Memphis |
| State/province |
TN |
| ZIP/Postal code |
38103 |
| Country |
USA |
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| Platforms (1) |
| GPL24247 |
Illumina NovaSeq 6000 (Mus musculus) |
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| Samples (1) |
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| Relations |
| BioProject |
PRJNA798919 |
