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| Status |
Public on Nov 26, 2009 |
| Title |
Genome-wide recognition of PML/RARa binding sites |
| Organism |
Homo sapiens |
| Experiment type |
Genome binding/occupancy profiling by genome tiling array
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| Summary |
PML/RARa is of crucial importance in acute promyelocytic leukemia (APL) both pathologically and therapeutically. Using a genome-wide approach, we identified in vivo PML/RARa binding sites in ZnSO4 treated PR9 cells. A total of 2,979 high quality binding sites were identified, representing 1,981 unique RefSeq genes. The supplementary bed file contains all 2,979 high quality PML-RARa binding sites reported in the paper.
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| Overall design |
RARa ChIP in ZnSO4 induced PR9 cells vs. Input in ZnSO4 induced PR9 cells.
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| Contributor(s) |
Wang K, Zhang J |
| Citation(s) |
20159610 |
| |
| Submission date |
Nov 25, 2009 |
| Last update date |
Jan 21, 2015 |
| Contact name |
Jiantao Shi |
| E-mail(s) |
jtshi@sibs.ac.cn
|
| Organization name |
Rui-Jin Hospital affiliated to Shanghai Jiao Tong University School of Medicine (RJH-SJTU-SM)
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| Street address |
197 Ruijin Rd II
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| City |
Shanghai |
| State/province |
Shanghai |
| ZIP/Postal code |
200025 |
| Country |
China |
| |
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| Platforms (1) |
| GPL5082 |
[Hs_PromPR] Affymetrix Human Promoter 1.0R Array |
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| Samples (1) |
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| This SubSeries is part of SuperSeries: |
| GSE19203 |
PML-RARa binding sites and their correlation with the gene expression in ATRA treated NB4 cells |
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| Relations |
| BioProject |
PRJNA123675 |