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Series GSE18644 Query DataSets for GSE18644
Status Public on Nov 09, 2010
Title Expression analysis in yeast model of Huntington's disease (HD)
Organism Saccharomyces cerevisiae
Experiment type Expression profiling by array
Summary Expressing a mutant fragment of huntingtin (Htt) in yeast produces several HD-relevant phenotypes. We used microarrays to study global change in expression induced by this mutant htt fragment.
Expression was also analysed in three suppressor deletion strains expressing a toxic mutant htt fragment: bna4Δ, mbf1Δ, and ume1Δ.
Overall design Yeast samples expressing either a wild-type or mutant htt fragment (Htt25Q or Htt103Q, respectively), and suppressor deletion strains expressing Htt103Q: bna4Δ, mbf1Δ, and ume1Δ.
Contributor(s) Tauber E, Giorgini F
Citation(s) 21044956
Submission date Oct 20, 2009
Last update date Jul 01, 2016
Contact name Eran Tauber
Organization name University of Leicester
Department Genetics
Street address University Road
City Leicester
ZIP/Postal code LE1 7RH
Country United Kingdom
Platforms (1)
GPL90 [YG_S98] Affymetrix Yeast Genome S98 Array
Samples (15)
GSM463308 Htt25Q rep.1
GSM463309 Htt25Q rep.2
GSM463310 Htt25Q rep.3
BioProject PRJNA121577

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE18644_RAW.tar 19.3 Mb (http)(custom) TAR (of CEL)
Raw data provided as supplementary file
Processed data included within Sample table

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