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| Status |
Public on May 21, 2010 |
| Title |
MicroRNA profiling shows different response to retinoids in estrogen-receptor positive and negative cells |
| Platform organisms |
Arabidopsis thaliana; Saccharomyces cerevisiae; Caenorhabditis elegans; Drosophila melanogaster; Gallus gallus; Macaca mulatta; Homo sapiens; Bos taurus; Mus musculus; Rattus norvegicus |
| Sample organism |
Homo sapiens |
| Experiment type |
Non-coding RNA profiling by array
|
| Summary |
This Series reports results of miRNA profiling of estrogen-receptor-positive (MCF7) and estrogen-receptor-negative (MDA-MB-231) cells.
Retinoic Acid (RA) induces mir-21 in MCF-7 but not in MDA-MB-231 cells.
MCF-7 and MDA-MB-231 cells were treated (or not) with retinoic acid (RA) and grown for either 6 hours or 48 hours.
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| |
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| Overall design |
miRNA profiling: Factorial design 2x2x2 'cube'; main factors: RA, cells, time; interactions: RA.cells, RA.time, cells.time, RA.cells.time.
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| |
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| Contributor(s) |
Terao M, Fratelli M, Tsykin A, Goodall GJ, Garattini E |
| Citation(s) |
21131358 |
| |
| Submission date |
Oct 19, 2009 |
| Last update date |
Mar 21, 2012 |
| Contact name |
Anna Tsykin |
| E-mail(s) |
anna.tsykin@adelaide.edu.au
|
| Phone |
61 8 8222 3479
|
| Organization name |
SA Pathology
|
| Department |
Hanson Institute
|
| Lab |
Centre for Cancer Research
|
| Street address |
Frome Road
|
| City |
Adelaide |
| State/province |
SA |
| ZIP/Postal code |
5000 |
| Country |
Australia |
| |
|
| Platforms (1) |
| GPL9472 |
Adelaide microarray facility Exiqon LNA miRNA microarray_version8.1 |
|
| Samples (24)
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| This SubSeries is part of SuperSeries: |
| GSE18693 |
Effects of retinoids on estrogen-receptor-positive and -negative breast carcinoma cells: mRNA and miRNA profiling |
|
| Relations |
| BioProject |
PRJNA123795 |
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