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Series GSE185274 Query DataSets for GSE185274
Status Public on Oct 31, 2021
Title aCGH from cells derived from adult individuals with acute lymphoblastic leukemia
Organism Homo sapiens
Experiment type Genome variation profiling by genome tiling array
Summary Chromosomal instability is a characteristic of cancer, in acute lymphoblastic leukemia, several genes with aberrations have been reported that are currently used as diagnostic tools, prognostics and are even part of the treatment.
The CGH microarrays performed in ten adult individuals with ALL, and the JURKAT and CEM cell lines, show that there are regions of shared loss on chromosomes 2, 9 and 14 and of gain on chromosomes 13 and 17 that are maintained in more than five of the samples.
 
Overall design Identification of regions of loss or gain in adult individuals with ALL and the JURKAT and CEM cell lines.
 
Contributor(s) Aguilar-Lemarroy A, Zapata-García JA
Citation(s) 36428851
Submission date Oct 04, 2021
Last update date Nov 28, 2022
Contact name Adriana Del Carmen Aguilar Lemarroy
E-mail(s) adry_al@outlook.com
Phone +52 3315207625
Organization name Centro de Investigación Biomédica de Occidente
Department División de Inmunología
Lab Inmunología
Street address Sierra Mojada 800, Independencia Oriente, 44340 Guadalajara, Jal.
City Guadalajara
State/province Jalisco
ZIP/Postal code 44340
Country Mexico
 
Platforms (1)
GPL14965 NimbleGen Human 3x720k Whole Genome CGH [100718_HG18_WG_CGH_v3.1_HX3]
Samples (12)
GSM5609915 JURKAT
GSM5609916 CEM
GSM5609917 M5
Relations
BioProject PRJNA768435

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE185274_RAW.tar 525.7 Mb (http)(custom) TAR (of GFF, TXT)
Processed data provided as supplementary file

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