|
| Status |
Public on Jan 27, 2022 |
| Title |
Effects of TNF on 'starved' primary hepatocytes |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
We generated transcriptional profiles of TNF-stimulated primary hepatocytes co-treated with PPARĪ± and GR ligands to mimic a condition of starvation.
|
| |
|
| Overall design |
Primary hepatocytes were cotreated with corticosterone (GR ligand), WY-14643 (PPARĪ± ligand), and TNF for 8 hours to assess the effect of TNF on 'starved' hepatocytes.
|
| |
|
| Contributor(s) |
Loft A, Schmidt SF, Herzig S |
| Citation(s) |
35120589 |
| |
| Submission date |
Sep 24, 2021 |
| Last update date |
May 02, 2022 |
| Contact name |
Anne Loft |
| E-mail(s) |
anlo@bmb.sdu.dk
|
| Organization name |
University of Southern Denmark
|
| Department |
Biochemistry & Molecular Biology
|
| Street address |
Campusvej 55
|
| City |
Odense M |
| ZIP/Postal code |
5230 |
| Country |
Denmark |
| |
|
| Platforms (1) |
| GPL24247 |
Illumina NovaSeq 6000 (Mus musculus) |
|
| Samples (6)
|
|
| This SubSeries is part of SuperSeries: |
| GSE147925 |
A Macrophage-Hepatocyte Glucocorticoid Receptor Axis Coordinates Fasting Ketogenesis |
|
| Relations |
| BioProject |
PRJNA766082 |
| SRA |
SRP338610 |
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