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Series GSE183954 Query DataSets for GSE183954
Status Public on Sep 11, 2022
Title Krüppel-like factors-4 and -2 are important regulators of joint tissue cells and protect against tissue destruction and inflammation in osteoarthritis [DRUG-seq]
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary We performed global gene expression analysis in Ad-KLF4-, Ad-EGFP- and non-transduced TC28a2 human chondrocyte cells, to study genes regulated by KLF4 comprehensively.
 
Overall design RNA samples from Ad-KLF4-, Ad-EGFP- and non-transduced TC28a2 cells with and without IL-1β stimulation were obtained (N = 7 replicates per condition; 42 samples in total). Then, digital RNA with pertUrbation of Genes (DRUG-seq) analysis was performed.
 
Contributor(s) Kawata M, Lotz MK, Natarajan P
Citation(s) 35534137, 37681413
Submission date Sep 11, 2021
Last update date Oct 19, 2023
Contact name Padma Natarajan
E-mail(s) ccbb@scripps.edu
Organization name The Scripps Research Institute
Department CCBB
Street address 10550 N.Torrey Pines Road
City La Jolla
State/province CA
ZIP/Postal code 92037
Country USA
 
Platforms (1)
GPL30173 NextSeq 2000 (Homo sapiens)
Samples (42)
GSM5574856 Non-Ad_IL-1b(-)_1 [01exp3X3HUMxsample12adNOADilNEGrp1-0NOADILNEG]
GSM5574857 Non-Ad_IL-1b(-)_2 [01exp3X3HUMxsample13adNOADilNEGrp2-0NOADILNEG]
GSM5574858 Non-Ad_IL-1b(-)_3 [01exp3X3HUMxsample14adNOADilNEGrp3-0NOADILNEG]
This SubSeries is part of SuperSeries:
GSE183956 Krüppel-like factors-4 and -2 are important regulators of joint tissue cells and protect against tissue destruction and inflammation in osteoarthritis
Relations
BioProject PRJNA762488
SRA SRP336656

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SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE183954_DEGs.xlsx 30.9 Mb (ftp)(http) XLSX
GSE183954_TPM.csv.gz 3.6 Mb (ftp)(http) CSV
GSE183954_raw_counts.csv.gz 1.6 Mb (ftp)(http) CSV
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Raw data are available in SRA
Processed data are available on Series record
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