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| Status |
Public on Sep 04, 2021 |
| Title |
Single-cell transcriptomics of human iPSC differentiation dynamics reveal a core molecular network of Parkinson’s disease |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Gabriela Novak et al. utilize scRNA-seq to investigate expression profiles in iPSC-derived midbrain dopaminergic neurons from Parkinson's disease patients or healthy controls. Their results suggest a core molecular network associated with Parkinson's disease pathology, and provide a future resource for investigation of this critical disorder.
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| |
|
| Overall design |
Single-cell RNA-Sequencing experiments were performed on a total of 12 samples.
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| |
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| Contributor(s) |
Novak G, Kyriakis D, Grzyb K, Bernini M, Rodius S, Dittmar G, Finkbeiner S, Skupin A |
| Citation(s) |
35027645, 38744869 |
| |
| Submission date |
Sep 02, 2021 |
| Last update date |
May 30, 2024 |
| Contact name |
Kamil Grzyb |
| E-mail(s) |
kamilgen@gmail.com, kamil.grzyb@uni.lu
|
| Organization name |
University of Luxembourg - LCSB
|
| Lab |
ICS
|
| Street address |
2, avenue de l'Université
|
| City |
Esch-sur-Alzette |
| ZIP/Postal code |
4365 |
| Country |
Luxembourg |
| |
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| Platforms (1) |
| GPL18573 |
Illumina NextSeq 500 (Homo sapiens) |
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| Samples (12)
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|
| Relations |
| BioProject |
PRJNA759784 |
| SRA |
SRP335353 |
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