|
| Status |
Public on Oct 14, 2022 |
| Title |
Role of Setd2 in regulatory T cells |
| Organism |
Mus musculus |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
Expression profiling by high throughput sequencing
|
| Summary |
This SuperSeries is composed of the SubSeries listed below.
To determine the molecular regulation of Tregs by Setd2, Spleen or large intestine Tregs (CD3+CD4+Foxp3-YFP+) were purified from littermate Foxp3Cre-YFPSetd2f/+ and Foxp3Cre-YFPSetd2f/f mice. Setd2-deficient and control Tregs were subjected to RNA-seq, RNA Polymerase II CUT&Tag or H3K27ac CUT&Tag analyses.
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| |
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| Overall design |
Refer to individual Series
|
| |
|
| Citation(s) |
36463230 |
| |
| Submission date |
Aug 26, 2021 |
| Last update date |
Dec 15, 2022 |
| Contact name |
Ju Qiu |
| Organization name |
Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences
|
| Street address |
320 Yueyang Road
|
| City |
Shanghai |
| ZIP/Postal code |
200031 |
| Country |
China |
| |
|
| Platforms (4)
|
| GPL19057 |
Illumina NextSeq 500 (Mus musculus) |
| GPL21103 |
Illumina HiSeq 4000 (Mus musculus) |
| GPL24247 |
Illumina NovaSeq 6000 (Mus musculus) |
|
| Samples (21)
|
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| This SuperSeries is composed of the following SubSeries:
|
| GSE182340 |
Role of Setd2 in regulatory T cells [H3K36me3 ChIP-seq] |
| GSE182837 |
Role of Setd2 in regulatory T cells [H3K27ac CUT&Tag] |
| GSE182839 |
Role of Setd2 in regulatory T cells [Pol II CUT&Tag] |
| GSE182841 |
Role of Setd2 in regulatory T cells [RNAseqTreg] |
| GSE215816 |
Role of Setd2 on regulatory T cells [RNA-seq SP Treg] |
|
| Relations |
| BioProject |
PRJNA758052 |
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