|
| Status |
Public on Apr 10, 2023 |
| Title |
Analysis of human TAp63 regulated genes in CD4+ T cells |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
By comparing the comprehensive gene expression profiles between human Th17 cells overexpressing TAp63 and those with TAp63 knockdown, FOXP3 was identified as one of the downregulated genes by TAp63
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| |
|
| Overall design |
Human Th17 cells were infected with retrovirus of LMP-non-silencing-IRES-Thy1.1 or LMP-hTAp63KD1-IRES-Thy1.1, and pMXs-IRES-NGFR or pMXs-hTAp63a-IRES-NGFR. Infected cells were sorted and subjected to RNA-sequence analysis.
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| |
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| Contributor(s) |
Suto A, Suga K, Tanaka S |
| Citation(s) |
37212280 |
| |
| Submission date |
Aug 03, 2021 |
| Last update date |
Jul 10, 2023 |
| Contact name |
Shigeru Tanaka |
| E-mail(s) |
stanaka@chiba-u.jp
|
| Organization name |
Chiba University
|
| Department |
Allergy and Clinical Immunology
|
| Street address |
1-8-1 Inohana
|
| City |
Chiba |
| ZIP/Postal code |
2608670 |
| Country |
Japan |
| |
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| Platforms (1) |
| GPL18460 |
Illumina HiSeq 1500 (Homo sapiens) |
|
| Samples (4)
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|
| Relations |
| BioProject |
PRJNA751975 |
| SRA |
SRP331144 |
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