|
| Status |
Public on Jul 30, 2021 |
| Title |
Aire regulates chromatin looping by evicting CTCF from domain boundaries and favoring accumulation of cohesin on super-enhancers [ChIP-seq] |
| Organism |
Mus musculus |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
ChIP-seq for proteins involved in Aire's functioning in Aire+/+ and Aire-/- mTECs
|
| |
|
| Overall design |
CD45-Ly51loMHCIIhi mTECs were FACS sorted and ChIP-seq was perfomed.
|
| |
|
| Contributor(s) |
Mathis D, Benoist C |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Jul 27, 2021 |
| Last update date |
Jul 31, 2021 |
| Contact name |
CBDM Lab |
| E-mail(s) |
cbdm@hms.harvard.edu
|
| Phone |
617-432-7747
|
| Organization name |
Harvard Medical School
|
| Department |
Microbiology and Immunobiology
|
| Lab |
CBDM
|
| Street address |
77 Avenue Louis Pasteur
|
| City |
Boston |
| State/province |
MA |
| ZIP/Postal code |
02215 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL19057 |
Illumina NextSeq 500 (Mus musculus) |
|
| Samples (12)
|
|
| This SubSeries is part of SuperSeries: |
| GSE180937 |
Aire regulates chromatin looping by evicting CTCF from domain boundaries and favoring accumulation of cohesin on super-enhancers |
|
| Relations |
| BioProject |
PRJNA750245 |
| SRA |
SRP330307 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE180934_RAW.tar |
1.0 Gb |
(http)(custom) |
TAR (of BIGWIG) |
| GSE180934_Readme.txt |
976 b |
(ftp)(http) |
TXT |
| GSE180934_merge_KO_CTCF.with.adapter.mapped_1align.sorted.uniq.RPKM.bigWig |
35.3 Mb |
(ftp)(http) |
BIGWIG |
| GSE180934_merge_KO_MED1.with.adapter.mapped_1align.sorted.uniq.RPKM.bigWig |
126.7 Mb |
(ftp)(http) |
BIGWIG |
| GSE180934_merge_KO_SMC1.with.adapter.mapped_1align.sorted.uniq.RPKM.bigWig |
167.7 Mb |
(ftp)(http) |
BIGWIG |
| GSE180934_merge_WT_CTCF.with.adapter.mapped_1align.sorted.uniq.RPKM.bigWig |
46.0 Mb |
(ftp)(http) |
BIGWIG |
| GSE180934_merge_WT_MED1.with.adapter.mapped_1align.sorted.uniq.RPKM.bigWig |
174.7 Mb |
(ftp)(http) |
BIGWIG |
| GSE180934_merge_WT_SMC1.with.adapter.mapped_1align.sorted.uniq.RPKM.bigWig |
166.8 Mb |
(ftp)(http) |
BIGWIG |
SRA Run Selector |
| Raw data are available in SRA |
| Processed data provided as supplementary file |
| Processed data are available on Series record |
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