|
| Status |
Public on Feb 19, 2010 |
| Title |
CpG site methylation of HCV-cirrhotic, HCV-HCC, and normal liver tissues |
| Organism |
Homo sapiens |
| Experiment type |
Methylation profiling by array
|
| Summary |
In this study we used a high-throughput method for assaying methylation of CpG sites simultaneously in a single sample for identifying differences in methylation observed in tissues ranging from normal liver to pre-neoplastic (cirrhosis) and neoplastic (HCC) states.
Since there are important clinical and prognostic differences among HCC patients due to etiology, this study was designed to focus on HCC due to HCV-infection, a more common etiology of HCC among Western countries
|
| |
|
| Overall design |
cross-sectional: 20 cirrhosis, 20 HCC, and 16 normal patients, 87 arrays
|
| |
|
| Contributor(s) |
Archer KJ, Mas VR, Maluf DG, Fisher RA |
| Citation(s) |
20165882 |
| |
| Submission date |
Sep 11, 2009 |
| Last update date |
Mar 21, 2012 |
| Contact name |
Kellie J. Archer |
| E-mail(s) |
archer.43@osu.edu
|
| Phone |
(614) 247-6167
|
| Organization name |
Ohio State University
|
| Department |
Division of Biostatistics
|
| Street address |
1841 Neil Ave
|
| City |
Columbus |
| State/province |
OH |
| ZIP/Postal code |
43210 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL9183 |
Illumina GoldenGate Methylation Cancer Panel I |
|
| Samples (87)
|
|
| Relations |
| BioProject |
PRJNA119353 |
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