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GEO accession:
Series GSE179416
Query DataSets for GSE179416
Status
Public on Jul 05, 2022
Title
Transcriptomic analyses of the effects of hepatic insulin signaling on hepatic gene expression in the PiZ mouse model of alpha-1-antitrypsin deficiency liver disease
Organism
Mus musculus
Experiment type
Expression profiling by high throughput sequencing
Summary
RNA-Seq data on livers from 4-5 month old male PiZ mice with or without genetic disruption of insulin receptor and FOXO1 hepatic expression
Overall design
Analyses of WT, Z, and ZZ mice, WT v LIRKO v LIRKO-FOXO1-KO
Contributor(s)
Rudnick DA
,
Cliften PF
,
Perlmutter DH
Citation(s)
35301011
Submission date
Jul 04, 2021
Last update date
Oct 19, 2022
Contact name
Paul Cliften
E-mail(s)
pcliften@wustl.edu
Organization name
Washington University
Department
Genetics
Lab
GTAC
Street address
4320 Forest Park Parkway
City
St. Louis
ZIP/Postal code
63108
Country
USA
Platforms (1)
GPL21493
Illumina HiSeq 3000 (Mus musculus)
Samples (43)
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GSM5417347
Sample 1468_LIRKO
GSM5417348
Sample 1474_LIRKO
GSM5417349
Sample 1483_LIRKO
GSM5417350
Sample 1600_LIRKO
GSM5417351
Sample 169_PiZ x LIRKO x F1KO (Z)
GSM5417352
Sample 170_PiZ x LIRKO x F1KO (Z)
GSM5417353
Sample 201_PiZ x LIRKO x F1KO (Z)
GSM5417354
Sample 206_PiZ x LIRKO x F1KO (Z)
GSM5417355
Sample 207_PiZ x LIRKO x F1KO (Z)
GSM5417356
Sample 1412_PiZ x LIRKO (Z)
GSM5417357
Sample 1427_PiZ x LIRKO (Z)
GSM5417358
Sample 1428_PiZ x LIRKO (Z)
GSM5417359
Sample 1450_PiZ x LIRKO (Z)
GSM5417360
Sample 1410_PiZ (Z)
GSM5417361
Sample 1411_PiZ (Z)
GSM5417362
Sample 1442_PiZ (Z)
GSM5417363
Sample 1443_PiZ (Z)
GSM5417364
Sample 1445_PiZ (Z)
GSM5417365
Sample 120_PiZ (Z*)
GSM5417366
Sample 182_PiZ (Z*)
GSM5417367
Sample 249_PiZ (Z*)
GSM5417368
Sample 251_PiZ (Z*)
GSM5417369
Sample 285_PiZ (Z*)
GSM5417370
Sample 1564_WT
GSM5417371
Sample 1586_WT
GSM5417372
Sample 1601_WT
GSM5417373
Sample 1682_PiZ (ZZ)
GSM5417374
Sample 1809_PiZ (ZZ)
GSM5417375
Sample 1846_PiZ (ZZ)
GSM5417376
Sample 1783_PiZ x LIRKO (ZZ)
GSM5417377
Sample 1810_PiZ x LIRKO (ZZ)
GSM5417378
Sample 1813_PiZ x LIRKO (ZZ)
GSM5417379
Sample 1855_PiZ x LIRKO (ZZ)
GSM5417380
Sample 1858_PiZ x LIRKO (ZZ)
GSM5417381
Sample 1876_PiZ x LIRKO (ZZ)
GSM5417382
Sample 1877_PiZ x LIRKO (ZZ)
GSM5417383
Sample 1564_WT_2
GSM5417384
Sample 1586_WT_2
GSM5417385
Sample 1601_WT_2
GSM5417386
Sample 1468_LIRKO_2
GSM5417387
Sample 1474_LIRKO_2
GSM5417388
Sample 1483_LIRKO_2
GSM5417389
Sample 1600_LIRKO_2
Relations
BioProject
PRJNA743657
SRA
SRP326867
Download family
Format
SOFT formatted family file(s)
SOFT
MINiML formatted family file(s)
MINiML
Series Matrix File(s)
TXT
Supplementary file
Size
Download
File type/resource
GSE179416_Hemizygous_all.gene_moderated_log2cpm.xls.gz
4.6 Mb
(ftp)
(http)
XLS
GSE179416_Homozygous_all.gene_moderated_log2cpm.xls.gz
3.2 Mb
(ftp)
(http)
XLS
SRA Run Selector
Raw data are available in SRA
Processed data are available on Series record
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