|
| Status |
Public on Jul 01, 2021 |
| Title |
Areca catechu-(Betel-nut)-induced whole transcriptome changes in a human monocyte cell line that may have relevance to diabetes and obesity; a pilot study |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Betel-nut consumption is the fourth most common addictive habit globally and there is good evidence linking the habit to obesity, type 2 diabetes (T2D) and the metabolic syndrome. The aim of our pilot study was to identify gene expression relevant to obesity, T2D and the metabolic syndrome using a genome-wide transcriptomic approach in a human monocyte cell line incubated with arecoline and its nitrosated products.
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| |
|
| Overall design |
3 THP1 samples treated with Arecoline and 3 samples treated with MNPA
|
| |
|
| Contributor(s) |
Hitman GA |
| Citation(s) |
34391409 |
| |
| Submission date |
Jun 29, 2021 |
| Last update date |
Aug 24, 2021 |
| Contact name |
Graham A Hitman |
| E-mail(s) |
g.a.hitman@qmul.ac.uk
|
| Organization name |
Queen Mary University of London
|
| Street address |
4 Newark St
|
| City |
London |
| ZIP/Postal code |
E1 2AT |
| Country |
United Kingdom |
| |
|
| Platforms (1) |
| GPL18573 |
Illumina NextSeq 500 (Homo sapiens) |
|
| Samples (6)
|
|
| Relations |
| BioProject |
PRJNA742406 |
| SRA |
SRP326141 |
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