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| Status |
Public on Mar 15, 2022 |
| Title |
Identification of differential expressed genes after HHEX/YAP/TAZ/TEAD knockdwon in colorectal cancer cells |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
We have identified HHEX as an oncogene to promote proliferation in colorectal cancer. To elucidate the potential mechanism of HHEX in colorectal cancer, RNA-seq analysis was performed in HCT116 cells to analyze differential expressed genes after HHEX knockdown.
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| Overall design |
HCT116 cells transiently expressing siNC control, siHHEX_1, siHHEX_2, siHHEX_3, siYAP/TAZ_1, siYAP/TAZ_2 or siTEAD1/2/3/4.
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| Contributor(s) |
Guo Y, Zhu Z, Liu C |
| Citation(s) |
36008411 |
| |
| Submission date |
Jun 09, 2021 |
| Last update date |
Aug 31, 2022 |
| Contact name |
Zhehui Zhu |
| E-mail(s) |
zhehuizhu0307@126.com
|
| Phone |
18217789586
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| Organization name |
Shanghai Jiao Tong University School of Medicine
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| Street address |
Kongjiang Road 1665, Shanghai
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| City |
Shanghai |
| State/province |
Shanghai |
| ZIP/Postal code |
200092 |
| Country |
China |
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| Platforms (1) |
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| Samples (8)
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| This SubSeries is part of SuperSeries: |
| GSE196333 |
Activation of the YAP-TEAD4-HHEX transcriptional complex by Casein Kinase 2 promotes tumorigenesis in colorectal cancer |
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| Relations |
| BioProject |
PRJNA736404 |
| SRA |
SRP323378 |
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