|
| Status |
Public on Jun 11, 2021 |
| Title |
Impaired antigen-specific memory B cell and plasma cell responses including lack of specific IgG upon SARS-CoV-2 BNT162b2 vaccination among Kidney Transplant and Dialysis patients |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
Other
|
| Summary |
Single cell transcriptome, cell-surface proterin, TCR and BCR sequencing of FACS-sorted activated T and B cells of the peripheral blood of patients vaccinated against COVID19 after kidney transplant transplantation
|
| |
|
| Overall design |
Sequencing of RNA, TCR and BCR was performed from FACS-sorted activated T cells (CD38+ HLA-DR+), memory B cells (CD38low CD27+) and plasmabolasts (CD38high CD27high) from the peripheral blood of four patients vaccinated against COVID19 after kidney transplantation, using the 10X Genomics platform with the Single Cell 5’ Library & Gel Bead Kit
|
| |
|
| Contributor(s) |
Schrezenmeier E, Ferreira-Gomes M, Guerra GM, Lehmann K, Heinrich F, Durek P, Mashreghi M |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Jun 09, 2021 |
| Last update date |
Jun 13, 2021 |
| Contact name |
Pawel Durek |
| E-mail(s) |
pawel.durek@drfz.de
|
| Organization name |
Deutsches Rheuma-Forschungszentrum
|
| Street address |
Charitéplatz 1
|
| City |
Berlin |
| ZIP/Postal code |
10117 |
| Country |
Germany |
| |
|
| Platforms (1) |
|
| Samples (4)
|
|
| Relations |
| BioProject |
PRJNA736300 |
| SRA |
SRP323339 |
Less...
More...