|
| Status |
Public on Jul 22, 2022 |
| Title |
RNA-sequencing of IRF5+ and IRF5- circulating monocytes from patients with Type-2 Diabetes |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Purpose: To characterise the transcriptomic landscape in monocytes associated with IRF5 expression
Methods: RNA sequencing from FACS sorted IRF5+ and IRF5- CD14+ monocytes
Results: Differential expression based on IRF5 postiivity provides insight into its roles in monocyte function and in type-2 diabetes
Conclusions: This study represents the first analyses of IRF5-dependent transcriptome in circulating monocytes from patients with Type-2 diabetes
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| |
|
| Overall design |
mRNA-sequencing of FACS sorted cells
|
| |
|
| Contributor(s) |
Orliaguet L, Alzaid F, Blugeon C, Lemoine S |
| Citation(s) |
36042203 |
| |
| Submission date |
Jun 05, 2021 |
| Last update date |
Oct 21, 2022 |
| Contact name |
Stephane Le Crom |
| Organization name |
IBENS
|
| Department |
Genomic Core Facility
|
| Street address |
46 rue Ulm
|
| City |
PARIS |
| ZIP/Postal code |
75230 |
| Country |
France |
| |
|
| Platforms (1) |
| GPL18573 |
Illumina NextSeq 500 (Homo sapiens) |
|
| Samples (48)
|
|
| Relations |
| BioProject |
PRJNA735395 |
| SRA |
SRP322863 |
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