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| Status |
Public on Apr 06, 2022 |
| Title |
miR-138 controls interneuron function and short-term memory |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
Using a miR-138 loss-of-function mouse model, a role for the brain enriched microRNA miR-138 in the regulation of inhibitory synaptic transmission and short-term memory formation was shown.
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| Overall design |
3 replicates each from total hippocampal RNA obtained from transgenic mice expressing either an inhibitory sponge transcript (sponge 138) or a control (ctrl) were subjected to polyA-RNA sequencing, followed by differential gene expression analysis.
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| Contributor(s) |
Daswani R, Dieterich C, Schratt G |
| Citation(s) |
35290180 |
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| Submission date |
May 06, 2021 |
| Last update date |
May 26, 2022 |
| Contact name |
Gerhard Schratt |
| E-mail(s) |
gerhard.schratt@hest.ethz.ch
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| Organization name |
ETH Zürich
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| Department |
D-HEST
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| Lab |
Systems Neuroscience
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| Street address |
Winterthurerstrasse 190
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| City |
Zürich |
| ZIP/Postal code |
8057 Zürich |
| Country |
Switzerland |
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| Platforms (1) |
| GPL13112 |
Illumina HiSeq 2000 (Mus musculus) |
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| Samples (6)
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| Relations |
| BioProject |
PRJNA727797 |
| SRA |
SRP318738 |