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Series GSE173498 Query DataSets for GSE173498
Status Public on Mar 09, 2022
Title Discovery and functional interrogation of the virus and host RNA interactome of SARS-CoV-2 proteins [eCLIP]
Organisms Homo sapiens; Chlorocebus sabaeus
Experiment type Other
Summary The coronavirus disease 2019 (COVID-19) pandemic was caused by severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2). Understanding the molecular functions of SARS-CoV-2 proteins is thus imperative to developing effective antiviral treatments. Here, we use enhanced crosslinking and immunoprecipitation to investigate SARS-CoV-2 protein interactions with viral and host RNAs. SARS-CoV-2 proteins, NSP8 and NSP12, are found to specifically bind to untranslated regions of the RNA viral genome, with NSP12 additionally binding to all transcription regulatory sequences. This provides evidence for their central roles in replication and transcription. Moreover, we discovered a potential site of NSP12 mediated genome recombination, which could explain the genetic diversity found in coronaviruses. SARS-CoV-2 proteins exogenously expressed in human lung epithelial cells bind to 4,281 unique host RNAs. Nine SARS-CoV-2 proteins upregulate target gene expression, including NSP12 which upregulates mitochondrial electron transport and N-linked glycosylation proteins. Furthermore, siRNA knockdown of NSP12-targeted proteins in human lung organoid cells demonstrates substantial antiviral effects. Conversely, NSP9 inhibits host gene expression via blocking mRNA export and dampens antiviral inflammation response such as interleukin 1α (IL1α) production. Our extensive viral protein-RNA interactome provides a catalog of potential therapeutic targets and offers insight into the etiology of COVID-19 as a safeguard against future pandemics.
 
Overall design Crosslinking and immunoprecipitation of SARS-CoV-2 protein bound RNA and sequencing from 2 technical replicates.
 
Contributor(s) Joy X, Jasmine M, En-Ching L, Brian Y, Danielle S, Jonathan S, Frederick T, Hsuan-Lin H, Chun-Yuan C, Kristopher B, Krysten J, Samuel P, Wenhao J, Rachael M, Elizabeth K, Phuong L, Kofman E, Anthony V, Yan-Hua L, Kevin D, Alexandra T, Yan S, Van Nostrand E, Sandra L, Yeo GW
Citation(s) 35233578, 35313591
Submission date Apr 28, 2021
Last update date Mar 31, 2022
Contact name Gene Yeo
E-mail(s) geneyeo@ucsd.edu
Organization name UCSD
Street address 2880 Torrey Pines Scenic Dr. Room 3805/Yeo Lab
City La Jolla
State/province CA
ZIP/Postal code 92037
Country USA
 
Platforms (2)
GPL11154 Illumina HiSeq 2000 (Homo sapiens)
GPL18769 Illumina HiSeq 2000 (Chlorocebus sabaeus)
Samples (147)
GSM5268670 NSP1 rep1 IP
GSM5268671 NSP1 rep2 IP
GSM5268672 NSP2 rep1 IP
This SubSeries is part of SuperSeries:
GSE173508 Discovery and functional interrogation of the virus and host RNA interactome of SARS-CoV-2 proteins
Relations
BioProject PRJNA725841
SRA SRP316737

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE173498_E_reproducible_peaks.bed.gz 14.1 Kb (ftp)(http) BED
GSE173498_M_reproducible_peaks.bed.gz 5.4 Kb (ftp)(http) BED
GSE173498_NSP1-1.vs.NSP1-2.bed.annotated_proxdist_miRlncRNA.WTfiltered.txt.gz 1.4 Kb (ftp)(http) TXT
GSE173498_NSP1-1.vs.NSP1-2.bed.gz 1.7 Kb (ftp)(http) BED
GSE173498_NSP14-1.vs.NSP14-2.bed.gz 12.2 Kb (ftp)(http) BED
GSE173498_NSP16-1.vs.NSP16-2.bed.annotated_proxdist_miRlncRNA.WTfiltered.txt.gz 734 b (ftp)(http) TXT
GSE173498_NSP16-1.vs.NSP16-2.bed.gz 811 b (ftp)(http) BED
GSE173498_N_reproducible_peaks.bed.gz 59.3 Kb (ftp)(http) BED
GSE173498_ORF10-1.vs.ORF10-2.bed.gz 3.9 Kb (ftp)(http) BED
GSE173498_ORF3a_reproducible_peaks.bed.gz 9.7 Kb (ftp)(http) BED
GSE173498_ORF6_reproducible_peaks.bed.gz 15.5 Kb (ftp)(http) BED
GSE173498_ORF7a_reproducible_peaks.bed.gz 13.8 Kb (ftp)(http) BED
GSE173498_SPIKE-1.vs.SPIKE-2.bed.gz 5.8 Kb (ftp)(http) BED
GSE173498_WT-high_reproducible_peaks.bed.gz 27.0 Kb (ftp)(http) BED
GSE173498_WT-low_reproducible_peaks.bed.gz 11.9 Kb (ftp)(http) BED
GSE173498_WTH-1.vs.WTH-2.bed.gz 3.8 Kb (ftp)(http) BED
GSE173498_WTL-1.vs.WTL-2.bed.gz 4.3 Kb (ftp)(http) BED
GSE173498_eCLIP2.E-1-IN.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.neg.bw 10.7 Mb (ftp)(http) BW
GSE173498_eCLIP2.E-1-IN.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.pos.bw 11.4 Mb (ftp)(http) BW
GSE173498_eCLIP2.E-1-IP.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.neg.bw 22.6 Mb (ftp)(http) BW
GSE173498_eCLIP2.E-1-IP.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.pos.bw 23.9 Mb (ftp)(http) BW
GSE173498_eCLIP2.E-1-IP.umi.r1.fq.genome-mappedSoSo.rmDupSo.peakClusters.normed.compressed.bed.gz 1.7 Mb (ftp)(http) BED
GSE173498_eCLIP2.E-2-IN.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.neg.bw 12.3 Mb (ftp)(http) BW
GSE173498_eCLIP2.E-2-IN.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.pos.bw 13.1 Mb (ftp)(http) BW
GSE173498_eCLIP2.E-2-IP.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.neg.bw 12.5 Mb (ftp)(http) BW
GSE173498_eCLIP2.E-2-IP.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.pos.bw 13.2 Mb (ftp)(http) BW
GSE173498_eCLIP2.E-2-IP.umi.r1.fq.genome-mappedSoSo.rmDupSo.peakClusters.normed.compressed.bed.gz 852.4 Kb (ftp)(http) BED
GSE173498_eCLIP2.E.bed.annotated_proxdist_miRlncRNA.WTfiltered.txt.gz 3.5 Kb (ftp)(http) TXT
GSE173498_eCLIP2.M-1-IN.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.neg.bw 9.7 Mb (ftp)(http) BW
GSE173498_eCLIP2.M-1-IN.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.pos.bw 10.2 Mb (ftp)(http) BW
GSE173498_eCLIP2.M-1-IP.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.neg.bw 6.6 Mb (ftp)(http) BW
GSE173498_eCLIP2.M-1-IP.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.pos.bw 7.0 Mb (ftp)(http) BW
GSE173498_eCLIP2.M-1-IP.umi.r1.fq.genome-mappedSoSo.rmDupSo.peakClusters.normed.compressed.bed.gz 591.5 Kb (ftp)(http) BED
GSE173498_eCLIP2.M-2-IN.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.neg.bw 6.0 Mb (ftp)(http) BW
GSE173498_eCLIP2.M-2-IN.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.pos.bw 6.3 Mb (ftp)(http) BW
GSE173498_eCLIP2.M-2-IP.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.neg.bw 6.6 Mb (ftp)(http) BW
GSE173498_eCLIP2.M-2-IP.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.pos.bw 6.9 Mb (ftp)(http) BW
GSE173498_eCLIP2.M-2-IP.umi.r1.fq.genome-mappedSoSo.rmDupSo.peakClusters.normed.compressed.bed.gz 579.2 Kb (ftp)(http) BED
GSE173498_eCLIP2.M.bed.annotated_proxdist_miRlncRNA.WTfiltered.txt.gz 6.6 Kb (ftp)(http) TXT
GSE173498_eCLIP2.N-1-IN.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.neg.bw 19.8 Mb (ftp)(http) BW
GSE173498_eCLIP2.N-1-IN.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.pos.bw 21.0 Mb (ftp)(http) BW
GSE173498_eCLIP2.N-1-IP.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.neg.bw 7.3 Mb (ftp)(http) BW
GSE173498_eCLIP2.N-1-IP.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.pos.bw 7.7 Mb (ftp)(http) BW
GSE173498_eCLIP2.N-1-IP.umi.r1.fq.genome-mappedSoSo.rmDupSo.peakClusters.normed.compressed.bed.gz 561.6 Kb (ftp)(http) BED
GSE173498_eCLIP2.N-2-IN.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.neg.bw 25.1 Mb (ftp)(http) BW
GSE173498_eCLIP2.N-2-IN.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.pos.bw 26.7 Mb (ftp)(http) BW
GSE173498_eCLIP2.N-2-IP.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.neg.bw 14.2 Mb (ftp)(http) BW
GSE173498_eCLIP2.N-2-IP.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.pos.bw 15.0 Mb (ftp)(http) BW
GSE173498_eCLIP2.N-2-IP.umi.r1.fq.genome-mappedSoSo.rmDupSo.peakClusters.normed.compressed.bed.gz 1000.2 Kb (ftp)(http) BED
GSE173498_eCLIP2.N.bed.annotated_proxdist_miRlncRNA.WTfiltered.txt.gz 125.2 Kb (ftp)(http) TXT
GSE173498_eCLIP2.ORF3a-1-IN.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.neg.bw 15.0 Mb (ftp)(http) BW
GSE173498_eCLIP2.ORF3a-1-IN.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.pos.bw 16.1 Mb (ftp)(http) BW
GSE173498_eCLIP2.ORF3a-1-IP.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.neg.bw 7.9 Mb (ftp)(http) BW
GSE173498_eCLIP2.ORF3a-1-IP.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.pos.bw 8.4 Mb (ftp)(http) BW
GSE173498_eCLIP2.ORF3a-1-IP.umi.r1.fq.genome-mappedSoSo.rmDupSo.peakClusters.normed.compressed.bed.gz 599.4 Kb (ftp)(http) BED
GSE173498_eCLIP2.ORF3a-2-IN.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.neg.bw 15.6 Mb (ftp)(http) BW
GSE173498_eCLIP2.ORF3a-2-IN.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.pos.bw 16.8 Mb (ftp)(http) BW
GSE173498_eCLIP2.ORF3a-2-IP.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.neg.bw 7.3 Mb (ftp)(http) BW
GSE173498_eCLIP2.ORF3a-2-IP.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.pos.bw 7.8 Mb (ftp)(http) BW
GSE173498_eCLIP2.ORF3a-2-IP.umi.r1.fq.genome-mappedSoSo.rmDupSo.peakClusters.normed.compressed.bed.gz 519.2 Kb (ftp)(http) BED
GSE173498_eCLIP2.ORF3a.bed.annotated_proxdist_miRlncRNA.WTfiltered.txt.gz 11.3 Kb (ftp)(http) TXT
GSE173498_eCLIP2.ORF6-1-IN.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.neg.bw 16.0 Mb (ftp)(http) BW
GSE173498_eCLIP2.ORF6-1-IN.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.pos.bw 17.1 Mb (ftp)(http) BW
GSE173498_eCLIP2.ORF6-1-IP.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.neg.bw 16.4 Mb (ftp)(http) BW
GSE173498_eCLIP2.ORF6-1-IP.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.pos.bw 17.4 Mb (ftp)(http) BW
GSE173498_eCLIP2.ORF6-1-IP.umi.r1.fq.genome-mappedSoSo.rmDupSo.peakClusters.normed.compressed.bed.gz 1.2 Mb (ftp)(http) BED
GSE173498_eCLIP2.ORF6-2-IN.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.neg.bw 15.1 Mb (ftp)(http) BW
GSE173498_eCLIP2.ORF6-2-IN.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.pos.bw 16.1 Mb (ftp)(http) BW
GSE173498_eCLIP2.ORF6-2-IP.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.neg.bw 15.5 Mb (ftp)(http) BW
GSE173498_eCLIP2.ORF6-2-IP.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.pos.bw 16.6 Mb (ftp)(http) BW
GSE173498_eCLIP2.ORF6-2-IP.umi.r1.fq.genome-mappedSoSo.rmDupSo.peakClusters.normed.compressed.bed.gz 1.2 Mb (ftp)(http) BED
GSE173498_eCLIP2.ORF6.bed.annotated_proxdist_miRlncRNA.WTfiltered.txt.gz 5.6 Kb (ftp)(http) TXT
GSE173498_eCLIP2.ORF7a-1-IN.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.neg.bw 29.6 Mb (ftp)(http) BW
GSE173498_eCLIP2.ORF7a-1-IN.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.pos.bw 31.2 Mb (ftp)(http) BW
GSE173498_eCLIP2.ORF7a-1-IP.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.neg.bw 6.7 Mb (ftp)(http) BW
GSE173498_eCLIP2.ORF7a-1-IP.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.pos.bw 7.0 Mb (ftp)(http) BW
GSE173498_eCLIP2.ORF7a-1-IP.umi.r1.fq.genome-mappedSoSo.rmDupSo.peakClusters.normed.compressed.bed.gz 689.6 Kb (ftp)(http) BED
GSE173498_eCLIP2.ORF7a-2-IN.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.neg.bw 18.1 Mb (ftp)(http) BW
GSE173498_eCLIP2.ORF7a-2-IN.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.pos.bw 19.0 Mb (ftp)(http) BW
GSE173498_eCLIP2.ORF7a-2-IP.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.neg.bw 8.0 Mb (ftp)(http) BW
GSE173498_eCLIP2.ORF7a-2-IP.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.pos.bw 8.3 Mb (ftp)(http) BW
GSE173498_eCLIP2.ORF7a-2-IP.umi.r1.fq.genome-mappedSoSo.rmDupSo.peakClusters.normed.compressed.bed.gz 848.2 Kb (ftp)(http) BED
GSE173498_eCLIP2.ORF7a.bed.annotated_proxdist_miRlncRNA.WTfiltered.txt.gz 14.9 Kb (ftp)(http) TXT
GSE173498_eCLIP2.WT-high-1-IN.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.neg.bw 20.0 Mb (ftp)(http) BW
GSE173498_eCLIP2.WT-high-1-IN.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.pos.bw 21.4 Mb (ftp)(http) BW
GSE173498_eCLIP2.WT-high-1-IP.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.neg.bw 15.8 Mb (ftp)(http) BW
GSE173498_eCLIP2.WT-high-1-IP.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.pos.bw 16.8 Mb (ftp)(http) BW
GSE173498_eCLIP2.WT-high-1-IP.umi.r1.fq.genome-mappedSoSo.rmDupSo.peakClusters.normed.compressed.bed.gz 1.2 Mb (ftp)(http) BED
GSE173498_eCLIP2.WT-high-2-IN.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.neg.bw 17.1 Mb (ftp)(http) BW
GSE173498_eCLIP2.WT-high-2-IN.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.pos.bw 18.3 Mb (ftp)(http) BW
GSE173498_eCLIP2.WT-high-2-IP.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.neg.bw 7.2 Mb (ftp)(http) BW
GSE173498_eCLIP2.WT-high-2-IP.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.pos.bw 7.6 Mb (ftp)(http) BW
GSE173498_eCLIP2.WT-high-2-IP.umi.r1.fq.genome-mappedSoSo.rmDupSo.peakClusters.normed.compressed.bed.gz 595.0 Kb (ftp)(http) BED
GSE173498_eCLIP2.WT-high.bed.annotated_proxdist_miRlncRNA.txt.gz 58.7 Kb (ftp)(http) TXT
GSE173498_eCLIP2.WT-low-1-IN.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.neg.bw 9.1 Mb (ftp)(http) BW
GSE173498_eCLIP2.WT-low-1-IN.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.pos.bw 9.7 Mb (ftp)(http) BW
GSE173498_eCLIP2.WT-low-1-IP.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.neg.bw 7.3 Mb (ftp)(http) BW
GSE173498_eCLIP2.WT-low-1-IP.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.pos.bw 7.7 Mb (ftp)(http) BW
GSE173498_eCLIP2.WT-low-1-IP.umi.r1.fq.genome-mappedSoSo.rmDupSo.peakClusters.normed.compressed.bed.gz 630.3 Kb (ftp)(http) BED
GSE173498_eCLIP2.WT-low-2-IN.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.neg.bw 11.8 Mb (ftp)(http) BW
GSE173498_eCLIP2.WT-low-2-IN.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.pos.bw 12.6 Mb (ftp)(http) BW
GSE173498_eCLIP2.WT-low-2-IP.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.neg.bw 7.8 Mb (ftp)(http) BW
GSE173498_eCLIP2.WT-low-2-IP.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.pos.bw 8.2 Mb (ftp)(http) BW
GSE173498_eCLIP2.WT-low-2-IP.umi.r1.fq.genome-mappedSoSo.rmDupSo.peakClusters.normed.compressed.bed.gz 548.3 Kb (ftp)(http) BED
GSE173498_eCLIP2.WT-low.bed.annotated_proxdist_miRlncRNA.txt.gz 25.5 Kb (ftp)(http) TXT
GSE173498_eCLIP2.nsp10-1-IN.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.neg.bw 12.1 Mb (ftp)(http) BW
GSE173498_eCLIP2.nsp10-1-IN.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.pos.bw 12.6 Mb (ftp)(http) BW
GSE173498_eCLIP2.nsp10-1-IP.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.neg.bw 9.4 Mb (ftp)(http) BW
GSE173498_eCLIP2.nsp10-1-IP.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.pos.bw 10.0 Mb (ftp)(http) BW
GSE173498_eCLIP2.nsp10-1-IP.umi.r1.fq.genome-mappedSoSo.rmDupSo.peakClusters.normed.compressed.bed.gz 919.2 Kb (ftp)(http) BED
GSE173498_eCLIP2.nsp10-2-IN.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.neg.bw 7.6 Mb (ftp)(http) BW
GSE173498_eCLIP2.nsp10-2-IN.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.pos.bw 10.4 Mb (ftp)(http) BW
GSE173498_eCLIP2.nsp10-2-IP.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.neg.bw 8.3 Mb (ftp)(http) BW
GSE173498_eCLIP2.nsp10-2-IP.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.pos.bw 8.8 Mb (ftp)(http) BW
GSE173498_eCLIP2.nsp10-2-IP.umi.r1.fq.genome-mappedSoSo.rmDupSo.peakClusters.normed.compressed.bed.gz 825.9 Kb (ftp)(http) BED
GSE173498_eCLIP2.nsp10.bed.annotated_proxdist_miRlncRNA.WTfiltered.txt.gz 25.3 Kb (ftp)(http) TXT
GSE173498_eCLIP2.nsp15-1-IN.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.neg.bw 12.9 Mb (ftp)(http) BW
GSE173498_eCLIP2.nsp15-1-IN.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.pos.bw 13.7 Mb (ftp)(http) BW
GSE173498_eCLIP2.nsp15-1-IP.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.neg.bw 14.8 Mb (ftp)(http) BW
GSE173498_eCLIP2.nsp15-1-IP.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.pos.bw 15.6 Mb (ftp)(http) BW
GSE173498_eCLIP2.nsp15-1-IP.umi.r1.fq.genome-mappedSoSo.rmDupSo.peakClusters.normed.compressed.bed.gz 1.0 Mb (ftp)(http) BED
GSE173498_eCLIP2.nsp15-2-IN.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.neg.bw 26.7 Mb (ftp)(http) BW
GSE173498_eCLIP2.nsp15-2-IN.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.pos.bw 28.4 Mb (ftp)(http) BW
GSE173498_eCLIP2.nsp15-2-IP.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.neg.bw 9.8 Mb (ftp)(http) BW
GSE173498_eCLIP2.nsp15-2-IP.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.pos.bw 10.4 Mb (ftp)(http) BW
GSE173498_eCLIP2.nsp15-2-IP.umi.r1.fq.genome-mappedSoSo.rmDupSo.peakClusters.normed.compressed.bed.gz 866.2 Kb (ftp)(http) BED
GSE173498_eCLIP2.nsp15.bed.annotated_proxdist_miRlncRNA.WTfiltered.txt.gz 7.1 Kb (ftp)(http) TXT
GSE173498_eCLIP2.nsp5-C145A-1-IN.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.neg.bw 7.6 Mb (ftp)(http) BW
GSE173498_eCLIP2.nsp5-C145A-1-IN.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.pos.bw 10.7 Mb (ftp)(http) BW
GSE173498_eCLIP2.nsp5_C145A-1-IP.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.neg.bw 6.8 Mb (ftp)(http) BW
GSE173498_eCLIP2.nsp5_C145A-1-IP.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.pos.bw 7.1 Mb (ftp)(http) BW
GSE173498_eCLIP2.nsp5_C145A-1-IP.umi.r1.fq.genome-mappedSoSo.rmDupSo.peakClusters.normed.compressed.bed.gz 554.0 Kb (ftp)(http) BED
GSE173498_eCLIP2.nsp5_C145A-2-IN.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.neg.bw 7.3 Mb (ftp)(http) BW
GSE173498_eCLIP2.nsp5_C145A-2-IN.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.pos.bw 7.6 Mb (ftp)(http) BW
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GSE173498_eCLIP3_3.nsp9-1-IN.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.pos.bw 29.5 Mb (ftp)(http) BW
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GSE173498_eCLIP3_3.nsp9-1-IP.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.pos.bw 20.9 Mb (ftp)(http) BW
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GSE173498_eCLIP3_3.nsp9-2-IN.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.neg.bw 27.7 Mb (ftp)(http) BW
GSE173498_eCLIP3_3.nsp9-2-IN.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.pos.bw 29.5 Mb (ftp)(http) BW
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GSE173498_eCLIP4_1.NSP14-2-IN.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.pos.bw 42.0 Mb (ftp)(http) BW
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GSE173498_eCLIP4_3.NSP8-1-IP.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.neg.bw 8.6 Mb (ftp)(http) BW
GSE173498_eCLIP4_3.NSP8-1-IP.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.pos.bw 9.0 Mb (ftp)(http) BW
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GSE173498_eCLIP4_3.NSP8-2-IN.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.neg.bw 13.3 Mb (ftp)(http) BW
GSE173498_eCLIP4_3.NSP8-2-IN.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.pos.bw 13.9 Mb (ftp)(http) BW
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GSE173498_eCLIP8_1.Vero_NSP12-2-IN.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.pos.bw 46.6 Mb (ftp)(http) BW
GSE173498_eCLIP8_1.Vero_NSP12-2-IP.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.neg.bw 16.6 Mb (ftp)(http) BW
GSE173498_eCLIP8_1.Vero_NSP12-2-IP.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.pos.bw 16.3 Mb (ftp)(http) BW
GSE173498_eCLIP8_1.Vero_NSP12-2-IP.umi.r1.fq.genome-mappedSoSo.rmDupSo.peakClusters.normed.compressed.bed.gz 1.0 Mb (ftp)(http) BED
GSE173498_eCLIP8_1.Vero_NSP8-1-IN.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.neg.bw 13.6 Mb (ftp)(http) BW
GSE173498_eCLIP8_1.Vero_NSP8-1-IN.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.pos.bw 13.7 Mb (ftp)(http) BW
GSE173498_eCLIP8_1.Vero_NSP8-1-IP.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.neg.bw 9.1 Mb (ftp)(http) BW
GSE173498_eCLIP8_1.Vero_NSP8-1-IP.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.pos.bw 9.1 Mb (ftp)(http) BW
GSE173498_eCLIP8_1.Vero_NSP8-1-IP.umi.r1.fq.genome-mappedSoSo.rmDupSo.peakClusters.normed.compressed.bed.gz 438.8 Kb (ftp)(http) BED
GSE173498_eCLIP8_1.Vero_NSP8-2-IN.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.neg.bw 19.0 Mb (ftp)(http) BW
GSE173498_eCLIP8_1.Vero_NSP8-2-IN.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.pos.bw 18.9 Mb (ftp)(http) BW
GSE173498_eCLIP8_1.Vero_NSP8-2-IP.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.neg.bw 8.1 Mb (ftp)(http) BW
GSE173498_eCLIP8_1.Vero_NSP8-2-IP.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.pos.bw 8.0 Mb (ftp)(http) BW
GSE173498_eCLIP8_1.Vero_NSP8-2-IP.umi.r1.fq.genome-mappedSoSo.rmDupSo.peakClusters.normed.compressed.bed.gz 360.1 Kb (ftp)(http) BED
GSE173498_eCLIP8_1.Vero_RbIgG_LMW-1-IN.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.neg.bw 10.4 Mb (ftp)(http) BW
GSE173498_eCLIP8_1.Vero_RbIgG_LMW-1-IN.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.pos.bw 10.5 Mb (ftp)(http) BW
GSE173498_eCLIP8_1.Vero_RbIgG_LMW-1-IP.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.neg.bw 15.8 Mb (ftp)(http) BW
GSE173498_eCLIP8_1.Vero_RbIgG_LMW-1-IP.umi.r1.fq.genome-mappedSoSo.rmDupSo.norm.pos.bw 15.6 Mb (ftp)(http) BW
GSE173498_eCLIP8b_Vero_N-1.vs.eCLIP8b_Vero_N-2.bed.gz 1.3 Kb (ftp)(http) BED
GSE173498_eCLIP8b_Vero_NSP12-1.vs.eCLIP8b_Vero_NSP12-2.bed.gz 31.6 Kb (ftp)(http) BED
GSE173498_eCLIP8b_Vero_NSP8-1.vs.eCLIP8b_Vero_NSP8-2.bed.gz 18.7 Kb (ftp)(http) BED
GSE173498_nsp10_reproducible_peaks.bed.gz 15.8 Kb (ftp)(http) BED
GSE173498_nsp11-1.vs.nsp11-2.bed.gz 8.0 Kb (ftp)(http) BED
GSE173498_nsp12-1.vs.nsp12-2.bed.gz 31.1 Kb (ftp)(http) BED
GSE173498_nsp13-1.vs.nsp13-2.bed.gz 6.9 Kb (ftp)(http) BED
GSE173498_nsp15_reproducible_peaks.bed.gz 17.8 Kb (ftp)(http) BED
GSE173498_nsp2-1.vs.nsp2-2.bed.gz 70.1 Kb (ftp)(http) BED
GSE173498_nsp3-1.vs.nsp3-2.bed.gz 62.7 Kb (ftp)(http) BED
GSE173498_nsp4-1.vs.nsp4-2.bed.gz 4.1 Kb (ftp)(http) BED
GSE173498_nsp5-1.vs.nsp5-2.bed.gz 70.2 Kb (ftp)(http) BED
GSE173498_nsp5_C145A_reproducible_peaks.bed.gz 6.2 Kb (ftp)(http) BED
GSE173498_nsp6-1.vs.nsp6-2.bed.gz 23.2 Kb (ftp)(http) BED
GSE173498_nsp7-1.vs.nsp7-2.bed.gz 29.0 Kb (ftp)(http) BED
GSE173498_nsp8-1.vs.nsp8-2.bed.gz 12.1 Kb (ftp)(http) BED
GSE173498_nsp9-1.vs.nsp9-2.bed.gz 42.5 Kb (ftp)(http) BED
GSE173498_orf3b-1.vs.orf3b-2.bed.gz 16.8 Kb (ftp)(http) BED
GSE173498_orf7b-1.vs.orf7b-2.bed.gz 19.9 Kb (ftp)(http) BED
GSE173498_orf8-1.vs.orf8-2.bed.gz 13.5 Kb (ftp)(http) BED
GSE173498_orf9b-1.vs.orf9b-2.bed.gz 7.4 Kb (ftp)(http) BED
GSE173498_orf9c-1.vs.orf9c-2.bed.gz 20.1 Kb (ftp)(http) BED
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