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Series GSE17307 Query DataSets for GSE17307
Status Public on Sep 01, 2009
Title GRE specific DNA-binding polyamide effect on dexamethasone-stimulated lung adenocarcinoma cell line
Organism Homo sapiens
Experiment type Expression profiling by array
Summary Analysis of dexamethasone-stimulated A549 lung adenocarcinoma epithelial cells treated with a glucocorticoid response (GR) element (GRE) specific DNA binding polyamide. Polyamide designed to target the sequence 5'-WGWWCW-3' and disrupt GR-mediated gene expression. Effects of the GR antagonist mifepristone also examined.
Overall design A549 cells were treated with compounds for 48 hours before RNA extraction and hybridization on Affymetrix microarrays.
Contributor(s) Muzikar KA, Nickols NG, Dervan PB
Citation(s) 19805343
Submission date Jul 24, 2009
Last update date Mar 25, 2019
Contact name Peter Dervan
Organization name California Institute of Technology
Street address 1200 East California Blvd
City Pasadena
State/province CA
ZIP/Postal code 91125
Country USA
Platforms (1)
GPL570 [HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Samples (15)
GSM433023 A549 non-treated control (1)
GSM433024 A549 non-treated control (2)
GSM433025 A549 non-treated control (3)
BioProject PRJNA118971

Download family Format
SOFT formatted family file(s) SOFTHelp
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Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE17307_RAW.tar 74.8 Mb (http)(custom) TAR (of CEL, CHP)
Processed data provided as supplementary file
Processed data included within Sample table

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