|
| Status |
Public on May 01, 2021 |
| Title |
Alterations in chromosome spatial compartmentalization classify prostate cancer progression [Hi-C] |
| Organism |
Homo sapiens |
| Experiment type |
Other
|
| Summary |
Through a systematic analysis of chromosome conformation capture in a cohort of cells that model cancer progression, San Martin et.al. find that rearrangement of the 3D genome structure in prostate cancer is a potential mechanism for disease exacerbation and that genome-wide compartment identity can classify cancer according to progression
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| |
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| Overall design |
Analysis of the 3D genomic structure of a cohort of cell lines in the continuum of prostate cancer, from normal to metastatic
Pleaes note that each processed data *tar file was generated from all replicates and is linked to the corresponding '*HiC-1' sample records.
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| |
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| Contributor(s) |
San Martin R, Das P, Dos Reis Marquez R, Yang X, McCord RP |
| Citation(s) |
34889941 |
| |
| Submission date |
Apr 14, 2021 |
| Last update date |
Jun 21, 2022 |
| Contact name |
Rebeca SanMartin |
| E-mail(s) |
rsanmart@utk.edu
|
| Organization name |
University of Tennessee Knoxville
|
| Street address |
1311 Cumberland Avenue
|
| City |
Knoxville |
| State/province |
TN |
| ZIP/Postal code |
37996 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL24676 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
| Samples (12)
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| This SubSeries is part of SuperSeries: |
| GSE172099 |
Alterations in chromosome spatial compartmentalization classify prostate cancer progression. |
|
| Relations |
| BioProject |
PRJNA722011 |
| SRA |
SRP314861 |
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