|
| Status |
Public on Feb 19, 2024 |
| Title |
PTIR1 acts as a suppressor of immunoproteasome and promotes cancer immune resistance |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Cancer cells evade host immune surveillance by virtue of poor immunogenicity. We identify a novel oncogene that acts as a promotor of tumor immune resistance, designated as PTIR1. Tumor-intrinsic PTIR1 is induced by RNA splicing and highly correlated with poor outcome of patients with cancer.
|
| |
|
| Overall design |
Study of tumor infiltration lymphocytes in Mock or PTIR1 expressing CT26 tumors using 10x scRNA-seq technologies.
|
| |
|
| Contributor(s) |
Song J, Lu D, Zhang X |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Mar 14, 2021 |
| Last update date |
Feb 19, 2024 |
| Contact name |
Jia Song |
| E-mail(s) |
songjia@bjmu.edu.cn
|
| Phone |
+18830053918
|
| Organization name |
Peking University
|
| Street address |
Peking University School of Medicine, 38 Xueyuan Road, Haidian District, Beijing
|
| City |
Beijing |
| State/province |
China |
| ZIP/Postal code |
100080 |
| Country |
China |
| |
|
| Platforms (1) |
| GPL24247 |
Illumina NovaSeq 6000 (Mus musculus) |
|
| Samples (2) |
|
| Relations |
| BioProject |
PRJNA714384 |
| SRA |
SRP310548 |
