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| Status |
Public on Feb 10, 2023 |
| Title |
RNA sequencing approaches to identify the differential expression gene in the mPFC with AAV-mediated Npas4 shRNA expression |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
Chronic social defeat stress induces anhedonia-like behavior deficits. We demonstrated that mPFC NPAS is requred for chronic social defeat stress-induced deficits in the sucrose preference and effort-based reward seeking behavior. We conducted the RNA-seq analysis for differential expression genes in the mouse mPFC samples of AAV-mediated Npas4 shRNA expression tissue.
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| Overall design |
Examination of mRNA expression in the mouse mPFC of AAV-mediated Npas4 shRNA and control scramble shRNA expression.
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| Contributor(s) |
Berto S, Hughes B, Taniguchi M, Cowan C |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
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| Submission date |
Jan 26, 2021 |
| Last update date |
Feb 12, 2023 |
| Contact name |
Makoto Taniguchi |
| E-mail(s) |
taniguch@musc.edu
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| Phone |
8437929772
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| Organization name |
Medical University of South Carolina
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| Street address |
173 Ashley ave, BSB410C
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| City |
Charleston |
| State/province |
SC |
| ZIP/Postal code |
29425 |
| Country |
USA |
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| Platforms (2) |
| GPL23479 |
BGISEQ-500 (Mus musculus) |
| GPL24247 |
Illumina NovaSeq 6000 (Mus musculus) |
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| Samples (8)
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| Relations |
| BioProject |
PRJNA695004 |
| SRA |
SRP303372 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE165586_GEO_Npas4_mPFC.txt.gz |
269.3 Kb |
(ftp)(http) |
TXT |
| GSE165586_RAW.tar |
62.9 Mb |
(http)(custom) |
TAR (of H5) |
SRA Run Selector |
| Raw data are available in SRA |
| Processed data are available on Series record |
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