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| Status |
Public on May 11, 2021 |
| Title |
Diet- and stress-induced changes of RNA in mouse heart |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
RNA-Seq data show that stress combined with a high-fat versus a fat-free diet, evokes greater changes in gene expression
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| |
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| Overall design |
Mice were fed either a fat-free (0 Kcal%) or a high-fat (60 Kcal%) diet for 4 days before subjecting them to a sham or transverse aortic constriction (TAC) surgeries. The mice were maintained on the same diet for another week, before they were assessed by echocardiography, the hearts isolated, RNA extracted, sequenced using Illumina NextSeq 500, and analyzed by DESeq2 at 10%FDR (adjusted p-value).
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| |
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| Contributor(s) |
Abdellatif M |
| Citation(s) |
33989779 |
| NIH grant(s) |
| Grant ID |
Grant title |
Affiliation |
Name |
| R01 HL146537 |
Transcriptional mechanisms in cardiac hypertrophy |
RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY--RBHS-NEW JERSEY MEDICAL SCHOOL |
Maha Abdellatif |
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| |
| Submission date |
Jan 19, 2021 |
| Last update date |
Jun 28, 2021 |
| Contact name |
Maha Abdellatif |
| E-mail(s) |
abdellma@njms.rutgers.edu
|
| Phone |
9739721254
|
| Organization name |
Rutgers-University
|
| Department |
Cell Biology and Molecular Medicine
|
| Street address |
185 S. Orange Ave.
|
| City |
Newark |
| State/province |
NJ |
| ZIP/Postal code |
07103 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL19057 |
Illumina NextSeq 500 (Mus musculus) |
|
| Samples (12)
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| Relations |
| BioProject |
PRJNA693240 |
| SRA |
SRP302342 |
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