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| Status |
Public on Mar 31, 2022 |
| Title |
Gene expression profiles of ears infected with Staphylococcus aureus at ZT4 |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
We analysed the gene expression profiles after infection of Staphylococcus aureus at ZT4 in CXCL14-KO mice. The group of genes categolized as GO defense response (GO: 006952) were upregulated upon a response to Staphylococcus aureus infection.
The expression of IL1b, Cxcl2, and Ccl3 were significantly suppressed in infected ear of Cxcl14-KO compared to that of WT.
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| Overall design |
PBS with or without 10^7 CFUs of S. aureus were injected intradermally into the pinnae of each ear of WT-C57BL/6 or Cxcl14-KO mice using a 30G insulin syringe at ZT4. Their ears were subjected to microarray andlysis after 3 hours post injection.
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| Contributor(s) |
Tanegashima K, Tsujihana K, Nishito Y, Okamura H, Hara T |
| Citation(s) |
35704759 |
| |
| Submission date |
Jan 15, 2021 |
| Last update date |
Jun 30, 2022 |
| Contact name |
Kosuke Tanegashima |
| E-mail(s) |
tanegashima-ks@igakuken.or.jp
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| Phone |
+81-3-5316-3130
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| Organization name |
Tokyo Metropolitan Institute of Medical Science
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| Lab |
Stem cell project
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| Street address |
2-1-6 Kamikitazawa
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| City |
Setagaya-ku |
| State/province |
Tokyo |
| ZIP/Postal code |
156-8506 |
| Country |
Japan |
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| Platforms (1) |
| GPL10333 |
Agilent-026655 Whole Mouse Genome Microarray 4x44K v2 (Feature Number version) |
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| Samples (4)
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| Relations |
| BioProject |
PRJNA692422 |
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