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| Status |
Public on Dec 14, 2023 |
| Title |
Transcriptome analysis among young and senescent fibroblasts expressing shLuciferase or shFbxo22 |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
We carried out the analysis using human skin fibrobllast HCA2 (MJ90) cells dox-inducible shLuciferase or shFbxo22. Cells were indcued to be senescent cells by treatment with 10 Gy. As a result, Gene set enrichment analysis revealed a significant increase in the expression of lysomal-related and autophagosomal genes in control cells, whereas this gene ontology was not increased in cells depleted of Fbxo22
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| Overall design |
Examination of young and senescent HCA2 cells expressing dox-inducible shLuciferase or shFbxo22.
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| Contributor(s) |
Johmura Y, Nakanishi M |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Dec 14, 2020 |
| Last update date |
Dec 14, 2023 |
| Contact name |
Satotaka Omori |
| E-mail(s) |
satotaka.omori.r@gmail.com
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| Phone |
0354495449
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| Organization name |
the university of Tokyo
|
| Street address |
shirokanedai, 4-6-1
|
| City |
Minato ku |
| State/province |
tokyo |
| ZIP/Postal code |
108-0071 |
| Country |
Japan |
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| Platforms (1) |
| GPL17303 |
Ion Torrent Proton (Homo sapiens) |
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| Samples (12)
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| Relations |
| BioProject |
PRJNA685149 |
| SRA |
SRP297908 |
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