 |
 |
GEO help: Mouse over screen elements for information. |
|
Status |
Public on Jan 01, 2021 |
Title |
Microarray analysis of human articular chondrocytes stimulated with Wnt3a in presence/absence of the CaMKII inhibitor KN93 |
Organism |
Homo sapiens |
Experiment type |
Expression profiling by array
|
Summary |
The scope of the analysis was to discriminate between CaMKII-dependent and independent targets of Wnt3a stimulation in human articular chondrocytes. Chondrocytes were isolated from preserved areas of the articular cartilage removed from 4 patients affected by osteoarthritis. The samples were stimulated with KN92 (inactive analogue of the CaMKII inhibitor KN93), KN92+Wnt3a and KN93+Wnt3a.
|
|
|
Overall design |
4 human donors, each condition tested either in singulate or duplicate within the individual biological samples. Total of 20 samples. KN92 stimulation used as control.
|
|
|
Contributor(s) |
Nalesso G, Dell'Accio F, Blighe K, Rana S |
Citation(s) |
33707504 |
|
Submission date |
Nov 24, 2020 |
Last update date |
Mar 23, 2021 |
Contact name |
Giovanna Nalesso |
E-mail(s) |
g.nalesso@surrey.ac.uk
|
Organization name |
University of Surrey
|
Street address |
Daphne Jackson Road
|
City |
Guildford |
ZIP/Postal code |
GU2 7AL |
Country |
United Kingdom |
|
|
Platforms (1) |
GPL25483 |
[HuGene-2_0-st] Affymetrix Human Gene 2.0 ST Array [gene symbol version] |
|
Samples (20)
|
GSM4932700 |
Human chondrocytes from donor 1 treated with KN92, tech repl 1 |
GSM4932701 |
Human chondrocytes from donor 2 treated with KN92+Wnt3a, tech repl 2 |
GSM4932702 |
Human chondrocytes from donor 2 treated with KN93+Wnt3a, tech repl 1 |
GSM4932703 |
Human chondrocytes from donor 2 treated with KN93+Wnt3a, tech repl 2 |
GSM4932704 |
Human chondrocytes from donor 3 treated with KN92 |
GSM4932705 |
Human chondrocytes from donor 3 treated with KN92+Wnt3a |
GSM4932706 |
Human chondrocytes from donor 3 treated with KN93+Wnt3a |
GSM4932707 |
Human chondrocytes from donor 4 treated with KN92, tech repl 1 |
GSM4932708 |
Human chondrocytes from donor 4 treated with KN92, tech repl 2 |
GSM4932709 |
Human chondrocytes from donor 4 treated with KN92+Wnt3a |
GSM4932710 |
Human chondrocytes from donor 4 treated with KN93+Wnt3a, tech repl 1 |
GSM4932711 |
Human chondrocytes from donor 1 treated with KN92, tech repl 2 |
GSM4932712 |
Human chondrocytes from donor 4 treated with KN93+Wnt3a, tech repl 2 |
GSM4932713 |
Human chondrocytes from donor 1 treated with KN92+Wnt3a, tech repl 1 |
GSM4932714 |
Human chondrocytes from donor 1 treated with KN92+Wnt3a, tech repl 2 |
GSM4932715 |
Human chondrocytes from donor 1 treated with KN93+Wnt3a, tech repl 1 |
GSM4932716 |
Human chondrocytes from donor 1 treated with KN93+Wnt3a, tech repl 2 |
GSM4932717 |
Human chondrocytes from donor 2 treated with KN92, tech repl 1 |
GSM4932718 |
Human chondrocytes from donor 2 treated with KN92, tech repl 2 |
GSM4932719 |
Human chondrocytes from donor 2 treated with KN92+Wnt3a, tech repl 1 |
|
Relations |
BioProject |
PRJNA680503 |
Supplementary file |
Size |
Download |
File type/resource |
GSE162076_RAW.tar |
154.3 Mb |
(http)(custom) |
TAR (of CEL) |
Processed data included within Sample table |
|
|
|
|
 |