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Series GSE16186 Query DataSets for GSE16186
Status Public on Jun 14, 2009
Title Gene expression profiles of human mesenchymal stem cells stimulated with canonical Wnt signaling
Organism Homo sapiens
Experiment type Expression profiling by array
Summary hMSC overexpressing activated or inactivated Wnt co-receptor LRP5 exhibit opposite phenotypes in osteogenesis and adipogenesis. To explore the underlying molecular mechanisms, we compared gene expression profiles upon Wnt3a stimulation and aimed at those genes functionally involved in determination of differentiation fate of hMSC.
Overall design Total RNA from hMSC overexpressing activated LRP5 (T253) or inactivated LRP5 (T244) treated with Wnt3a condition medium for 1 hour or 24 hours was compared with those treated with control condition medium. 3 replicates per condition.

The supplementary file 'GSE16186_non-normalized_data.txt' contains non-normalized data for Samples GSM406367-GSM406390.
Contributor(s) Qiu W, Hu Y, Li N, Chen W, Kassem M
Citation(s) 20223822
Submission date May 20, 2009
Last update date Mar 21, 2012
Contact name na li
Phone 0049-30-94063043
Lab AG chen
Street address Robert-Rössle-Straße 10
City berlin
ZIP/Postal code 13125
Country Germany
Platforms (1)
GPL5104 Sentrix HumanRef-8 v2 Expression BeadChip
Samples (24)
GSM406367 T244 Co 1h rep1
GSM406368 T244 Co 1h rep2
GSM406369 T244 Co 1h rep3
BioProject PRJNA115077

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE16186_non-normalized_data.txt.gz 3.1 Mb (ftp)(http) TXT
Raw data is available on Series record
Processed data included within Sample table
Raw data provided as supplementary file

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