|
| Status |
Public on May 16, 2022 |
| Title |
ETV6-NCOA2 expression profile in T/M mixed-phenotype acute leukemia [ETV6-NCOA2 human] |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Exparession profiling of ETV6-NCOA2 at different stages of disease dEmpty vectorelopment: CD34 cord blood cells transduced with ETV6-NCOA2-GFP or with empty vector-GFP, CD34 cord blood cells transduced with ETV6-NCOA2-NGFR or ETV6-NCOA2-NGFR + NOTCH1-L1601PdP-GFP and transplanted in NSGS mice, and ETV6-NCOA2 patient derived xenografts.
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| |
|
| Overall design |
Expression profiling of ETV6-NCOA2 in human: CD34 positive cord blood cells transduced with ETV6-NCOA2 or empty vector, cultured five days in-vitro (n=3), ETV6-NCOA2 (n=3) or ETV6-NCOA2+NOTCH1-L1601PdP (n=5) transduced in CD34 positive cord blood cells and transplanted in NSGS mice, or ETV6-NCOA2 patient-derived xenografts (n=4).
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| |
|
| Contributor(s) |
Izraeli S, Fishman H |
| Citation(s) |
34624096 |
| |
| Submission date |
Nov 18, 2020 |
| Last update date |
May 16, 2022 |
| Contact name |
Gilgi Friedlander |
| Organization name |
Weizmann Institute of Science
|
| Street address |
Hertzel st
|
| City |
Rehovot |
| ZIP/Postal code |
76100 |
| Country |
Israel |
| |
|
| Platforms (1) |
| GPL16791 |
Illumina HiSeq 2500 (Homo sapiens) |
|
| Samples (17)
|
| GSM4912892 |
ETV6-NCOA2 patient derived xenograft_1 [EN2_PDX_3] |
| GSM4912893 |
ETV6-NCOA2 patient derived xenograft_2 [EN2_PDX_1] |
| GSM4912894 |
ETV6-NCOA2 patient derived xenograft_3 [EN2_PDX_2] |
|
| This SubSeries is part of SuperSeries: |
| GSE162338 |
ETV6-NCOA2 expression in CD34 positive cord blood cells |
|
| Relations |
| BioProject |
PRJNA679212 |
| SRA |
SRP293069 |
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