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Series GSE161524 Query DataSets for GSE161524
Status Public on Nov 17, 2020
Title Transcriptional dynamics of ricin-induced ARDS
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary We report the presence of pathologic states of epithelial, mesenchymal and vascular endothelial cells and molecular programs involved in immunopathological progression. We also report the transcriptionally functional diversity of neutrophils and identify a previously undetected neutrophil subset undergoing transdifferentiated process. Cell–cell interaction analysis reveal vascular mural cells as potential crosstalk hubs in pulmonary communication network.
 
Overall design Examination of dynamic transcriptional signatures of lung structural and immune populations during the early stages of ARDS
 
Contributor(s) Su D, Yang H, Zhou D
Citation(s) 37933384
Submission date Nov 16, 2020
Last update date Dec 01, 2023
Contact name Duo Su
E-mail(s) duosu@hotmail.com
Organization name Beijing Institute of Microbiology and Epidemiology
Lab State Key Laboratory of Pathogen and Biosecurity
Street address Street Dongdajie
City Beijing
ZIP/Postal code 100071
Country China
 
Platforms (1)
GPL16417 Illumina MiSeq (Mus musculus)
Samples (4)
GSM4909199 Lung PBS Sham scRNA-seq
GSM4909200 Lung Ricin 8h scRNA-seq
GSM4909201 Lung Ricin 24h scRNA-seq
Relations
BioProject PRJNA678642
SRA SRP292697

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE161524_RAW.tar 472.4 Mb (http)(custom) TAR (of TAR)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data are available on Series record

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