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| Status |
Public on Sep 08, 2020 |
| Title |
mTOR inhibition by INK128 extends ovarian functions in aging and premature aging mice following germline stem cell transplantation |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Germline stem cell transplantation in combination with mTOR inhibition by INK128 can improve and extend ovarian and endocrine functions of aging and particularly premature aging mice.
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| Overall design |
We collected the transplanted rOvaries of premature aging miceļ¼compared the groups fed with INK128 and those without INK128 , and performed RNA sequencing analysis to explore the mechanism of INK128 extending ovarian function
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| Contributor(s) |
Heng D, Sheng X, Tian C, Li J, Liu L, Gou M, Liu L |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Sep 02, 2020 |
| Last update date |
Sep 09, 2020 |
| Contact name |
Heng Dai |
| E-mail(s) |
1120180417@mail.nankai.edu.cn
|
| Phone |
15201113160
|
| Organization name |
NanKai University
|
| Street address |
NanKai District NanKai University
|
| City |
TianJin |
| State/province |
TianJin |
| ZIP/Postal code |
300071 |
| Country |
China |
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| Platforms (1) |
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| Samples (4)
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| Relations |
| BioProject |
PRJNA660943 |
| SRA |
SRP279725 |
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