|
| Status |
Public on Aug 22, 2020 |
| Title |
Stem cell-derived neutrophil-primed progenitors prevent lethal infection |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
We show that engineered neutrophil-primed progenitors derived from human induced pluripotent stem cells (NeuPs-XL) can produce functional neutrophil-like cells (NeuCs-XL) that can act promptly in vivo against lethal bacterial infections at a clinically applicable scale. We performed global gene expression profiling of NeuPs-XL and NeuCs-XL with or without LPS stimulation.
|
| |
|
| Overall design |
gene expression profiling of NeuPs-XL and NeuCs-XL with or without LPS stimulation
|
| |
|
| Contributor(s) |
Ito Y, Miyauchi M, Nakahara F, Hino T, Nakamura F, Iwasaki Y, Kawagoshi T, Koya J, Yoshimi A, Arai S, Kagoya Y, Kurokawa M |
| Citation(s) |
34587247 |
| |
| Submission date |
Aug 21, 2020 |
| Last update date |
Apr 17, 2023 |
| Contact name |
Yusuke Ito |
| E-mail(s) |
yuusuitou-tky@umin.ac.jp
|
| Phone |
+81333531211
|
| Organization name |
Keio University
|
| Department |
Division of Tumor Immunology
|
| Street address |
35 Shinanomachi
|
| City |
Shinjuku-ku |
| State/province |
Tokyo |
| ZIP/Postal code |
1608582 |
| Country |
Japan |
| |
|
| Platforms (1) |
|
| Samples (9)
|
|
| Relations |
| BioProject |
PRJNA658513 |
| SRA |
SRP278366 |
Less...
More...