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Series GSE155327 Query DataSets for GSE155327
Status Public on Jul 30, 2020
Title Expression data from embryonic mouse spinal cords from NFIX knockout and wild-type mice.
Organism Mus musculus
Experiment type Expression profiling by array
Summary The generation of cellular identity and diversity within the developing spinal cord is critically dependent on networks of gene expression controlled by transcription factors, such as Nuclear Factor One X (NFIX). NFIX has been identified as an important factor in promoting astrocyte formation during embryonic mouse spinal cord development.
To gain a more comprehensive understanding of the transcriptional landscape controlled by NFIX within the developing spinal cord, here we performed microarray analysis on E14.5 wild-type and Nfix-/- mouse spinal cords, the age at which the expression of NFIX by neural progenitor cells lining the spinal central canal is strongest.
 
Overall design Whole spinal cords from Nfix-/- mouse embryos at E14.5 (and wild-type littermate controls; n=4) were dissected for RNA extraction and hybridization on an Affymetrix Mouse Transcriptome Analysis microarray.
 
Contributor(s) Matuzelski E, Piper M
Citation(s) 32938475
Submission date Jul 29, 2020
Last update date Oct 02, 2020
Contact name Michael Piper
E-mail(s) m.piper@uq.edu.au
Organization name University of Queensland
Department School of Biomedical Science
Street address Building 81, University of Queensland, St Lucia
City Brisbane
State/province QLD
ZIP/Postal code 4067
Country Australia
 
Platforms (1)
GPL20775 [MTA-1_0] Affymetrix Mouse Transcriptome Array 1.0 [transcript (gene) CSV version]
Samples (8)
GSM4699179 spinal cord at E14_Nfix-/-_biological rep 1
GSM4699180 spinal cord at E14_Nfix-/-_biological rep 2
GSM4699181 spinal cord at E14_Nfix-/-_biological rep 3
Relations
BioProject PRJNA649417

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Supplementary file Size Download File type/resource
GSE155327_RAW.tar 202.8 Mb (http)(custom) TAR (of CEL, CHP)
Raw data provided as supplementary file
Processed data included within Sample table
Processed data provided as supplementary file

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