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| Status |
Public on Jan 01, 2021 |
| Title |
Expression data of microRNA from human stem cells from apical papilla |
| Platform organism |
synthetic construct |
| Sample organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
Osteo/odontogenic differentiation is a key process of human stem cells from apical papilla (SCAP) in tooth root development. Emerging evidence indicates microRNAs (miRNAs) play diverse roles in osteogenesis. However, their functions in osteo/odontogenic differentiation of SCAP remain to be elucidated.
We used miRNA microarray to analysis differentially expressed miRNAs in order to investigate the role of miRNAs in SCAP osteo/odontogenic differentiation and underlying mechanism.
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| Overall design |
Stem cells from apical papilla of human immature third molar were selected for RNA extraction and hybridization on Affymetrix microarrays. We sought to obtain homogeneous stem cells from apical papilla (SCAP) at each osteogenic differentiation stage in order to increase the temporal resolution of expression profiles. To that end, we selected SCAP at two time-points: before osteogenic differentiation (c) and osteogenic differentiation for 7 days (k).Biological replicates: 3 control replicates (1c, 2c, 3c), 3 testing replicates (1k, 2k, 3k).
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| Contributor(s) |
Wang Y, Liu J, Du J |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
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| Submission date |
Jul 15, 2020 |
| Last update date |
Jan 04, 2021 |
| Contact name |
Junqing Liu |
| Organization name |
Shandong University
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| Street address |
No.44-1 Wenhua Road West
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| City |
Jinan |
| ZIP/Postal code |
250012 |
| Country |
China |
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| Platforms (1) |
| GPL19117 |
[miRNA-4] Affymetrix Multispecies miRNA-4 Array |
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| Samples (6)
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| Relations |
| BioProject |
PRJNA646393 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE154466_RAW.tar |
4.2 Mb |
(http)(custom) |
TAR (of CEL) |
| Processed data included within Sample table |
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