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Status |
Public on Jul 11, 2020 |
Title |
Genetic profiling of fetal human hepatocytes immortalized with hTERT |
Organism |
Homo sapiens |
Experiment type |
Expression profiling by array
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Summary |
The successfully immortalized fetal human hepatocytes expressed large numbers of hepatic and other genes. The expression of gene groups and networks was maintained over extended culture.
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Overall design |
Cells were examined with Affimetrix microarrays for gene expression over prolonged passaging after immortalization. The major goal was to demonstrate genetic stability.
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Contributor(s) |
Gupta S |
Citation missing |
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Submission date |
Jul 10, 2020 |
Last update date |
Jun 02, 2023 |
Contact name |
Sanjeev Gupta |
E-mail(s) |
sanjeev.gupta@einsteinmed.org
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Organization name |
Albert Einstein College of Medicine
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Department |
Medicine
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Street address |
1300 Morris Park Ave.
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City |
Bronx |
State/province |
NY |
ZIP/Postal code |
10461 |
Country |
USA |
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Platforms (1) |
GPL571 |
[HG-U133A_2] Affymetrix Human Genome U133A 2.0 Array |
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Samples (18)
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GSM4665789 |
P0A: fetal hepatocytes in initial culture,biological rep1 |
GSM4665790 |
P0B: fetal hepatocytes in initial culture,biological rep2 |
GSM4665791 |
P0C: fetal hepatocytes in initial culture,biological rep3 |
GSM4665792 |
P1A: fetal hepatocytes in the 1st passage, biological rep1 |
GSM4665793 |
P1B: fetal hepatocytes in the 1st passage, biological rep2 |
GSM4665794 |
P1C: fetal hepatocytes in the 1st passage, biological rep3 |
GSM4665795 |
P8A: fetal hepatocytes in the 8th passage, biological rep1 |
GSM4665796 |
P8B: fetal hepatocytes in the 8th passage, biological rep2 |
GSM4665797 |
P8C: fetal hepatocytes in the 8th passage, biological rep3 |
GSM4665798 |
P22-1: hTERT-FH-B, passage 22, biological rep1 |
GSM4665799 |
P22-2: hTERT-FH-B, passage 22, biological rep2 |
GSM4665800 |
P22-3: hTERT-FH-B, passage 22, biological rep3 |
GSM4665801 |
P58-1: hTERT-FH-B, passage 58, biological rep1 |
GSM4665802 |
P58-2: hTERT-FH-B, passage 58, biological rep2 |
GSM4665803 |
P58-3: hTERT-FH-B, passage 58, biological rep3 |
GSM4665804 |
P113-1: hTERT-FH-B, passage 113, biological rep1 |
GSM4665805 |
P113-2: hTERT-FH-B, passage 113, biological rep2 |
GSM4665806 |
P113-3: hTERT-FH-B, passage 113, biological rep3 |
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Relations |
BioProject |
PRJNA645400 |
Supplementary file |
Size |
Download |
File type/resource |
GSE154198_RAW.tar |
38.0 Mb |
(http)(custom) |
TAR (of CEL, CHP) |
Processed data included within Sample table |
Processed data provided as supplementary file |
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