|
| Status |
Public on Jul 08, 2020 |
| Title |
Splicing factor Ybx1 maintains persistent Jak2-mutated neoplasms via Mknk1-ERK-signaling persistent clones in Jak2-mutated neoplasms |
| Organism |
Mus musculus |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
Inactivation of Ybx1 results in RNA mis-splicing, retained intron enrichment and disruption of the transcriptional and post-translational control of extracellular signal-regulated kinase (ERK) signaling
|
| |
|
| Overall design |
Examination of Ybx1 DNAbinding sites in BaF3 V617Fcells
|
| |
|
| Contributor(s) |
Jayavelu AK, Mann M, Heidel FH |
| Citation(s) |
33239784 |
| |
| Submission date |
Jul 08, 2020 |
| Last update date |
Dec 03, 2020 |
| Contact name |
Sung-Huan Yu |
| E-mail(s) |
shyu@biochem.mpg.de
|
| Organization name |
Max Planck Institute
|
| Street address |
Am Klopferspitz 18
|
| City |
Planegg |
| ZIP/Postal code |
81251 |
| Country |
Germany |
| |
|
| Platforms (1) |
| GPL19057 |
Illumina NextSeq 500 (Mus musculus) |
|
| Samples (6)
|
|
| Relations |
| BioProject |
PRJNA644892 |
| SRA |
SRP270934 |
Less...
More...