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| Status |
Public on Jul 09, 2020 |
| Title |
Gene expression profiles in rat lung following intratracheal instillation with cellulose nanofibrils and multi-walled carbon nanotubes |
| Organism |
Rattus norvegicus |
| Experiment type |
Expression profiling by array
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| Summary |
To evaluate the biological effects at the transcriptional level of manufactured nanomaterials, whole genome microarray analysis of rat lungs intratracheally instilled with cellulose nanofibrils (CNFs) with different physicochemical properties or multi-walled carbon nanotubes (MWCNTs) were performed.
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| Overall design |
Rats intratracheally instilled with three types of CNFs (CNF1, CNF2, and CNF3), MWCNTs (0.5, 1.0 and 2.0 mg/kg), and their solvents as vehicle control were dissected at 1day, 3 days, 7 days, 30 days, and 90 days post-instillation, and then the lungs were used for microarray analysis.
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| Contributor(s) |
Fujita K, Obara S |
| Citation |
https://doi.org/10.1007/s10570-021-03943-2
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| Submission date |
Jul 08, 2020 |
| Last update date |
May 28, 2021 |
| Contact name |
Katsuhide Fujita |
| E-mail(s) |
ka-fujita@aist.go.jp
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| Organization name |
National Institute of Advanced Industrial Science and Technology
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| Department |
Research Institute of Science for Safety and Sustainability
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| Street address |
16-1 Onogawa
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| City |
Tsukuba |
| ZIP/Postal code |
3058569 |
| Country |
Japan |
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| Platforms (1) |
| GPL7294 |
Agilent-014879 Whole Rat Genome Microarray 4x44K G4131F (Probe Name version) |
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| Samples (80)
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| Relations |
| BioProject |
PRJNA644821 |
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