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Series GSE153894 Query DataSets for GSE153894
Status Public on Jun 25, 2021
Title Negative correlation of Pax3:Foxo1 expression at the single-cell-level with tumorigenic potential in rhabdomyosarcoma
Organism Mus musculus
Experiment type Expression profiling by array
Summary In mouse Myf6Cre,Pax3:Foxo1,p53 rhabdomyosarcoma (RMS) cells, expression of Pax3:Foxo1 (P3F) is directed by the Pax3 promoter and coupled to an eYFP fluorescent marker.
YFPlow/P3Flow mouse RMS cells differentially expressed transcripts involved in extracellular matrix interaction, reorganized their actin cytoskeleton to promote adhesion/ migration and exhibited higher tumor-propagating capacity in limiting dilution analyses.
 
Overall design Total RNA was isolated from YFPlow/P3Flow, YFPhigh/P3Fhigh and unfractionated low-passage mouse RMS cells (U23674) and analyzed by Clariom S Assays, mouse arrays (Affymetrix 902931).
 
Contributor(s) Regina C, Andrieux G, Boerries M, Keller C, Hettmer S
Citation(s) 34187933
Submission date Jul 06, 2020
Last update date Jul 06, 2021
Contact name Geoffroy Andrieux
Organization name University clinics Freiburg
Street address Breisacherstr 153
City Freiburg
ZIP/Postal code 79110
Country Germany
 
Platforms (1)
GPL23038 [Clariom_S_Mouse] Affymetrix Clariom S Assay, Mouse (Includes Pico Assay)
Samples (12)
GSM4658231 P6
GSM4658232 P5
GSM4658233 P4
Relations
BioProject PRJNA644444

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Supplementary file Size Download File type/resource
GSE153894_RAW.tar 12.9 Mb (http)(custom) TAR (of CEL)
Raw data provided as supplementary file
Processed data included within Sample table

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