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| Status |
Public on Jan 02, 2021 |
| Title |
Gene expression profile of bladder cancer cell lines treated with Mitomycin C |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Mitomycin C (MMC) is the gold standard treatment for non-muscle invasive bladder cancer (NMIBC). We aimed to evaluate in bladder cancer cell lines (T24, 5637, TCC-SUP and CLS-439) the transcriptomic response to MMC treatment. We used Gene Set Enrichment Analysis (GSEA) to identify biological processes and pathways modulated by MMC treatment.
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| Overall design |
mRNA profiles of T24, 5637, TCC-SUP and CLS-439 bladder cancer cell lines treated or not with Mitomicyn C (3 biological replicates for each condition)
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| |
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| Contributor(s) |
Oresta B, Braga D, Rescigno M |
| Citation(s) |
33408185 |
| |
| Submission date |
May 30, 2020 |
| Last update date |
Jan 08, 2021 |
| Contact name |
Daniele Braga |
| E-mail(s) |
daniele.braga@humanitasresearch.it
|
| Organization name |
Humanitas Clinical and Research Center
|
| Lab |
Laboratory of Mucosal Immunology and Microbiota
|
| Street address |
Via Manzoni 56
|
| City |
Rozzano (MI) |
| ZIP/Postal code |
20089 |
| Country |
Italy |
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| Platforms (1) |
| GPL18573 |
Illumina NextSeq 500 (Homo sapiens) |
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| Samples (24)
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| Relations |
| BioProject |
PRJNA636096 |
| SRA |
SRP265359 |
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