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GEO accession:
Series GSE148695
Query DataSets for GSE148695
Status
Public on Oct 05, 2021
Title
SATB2 preserves colon stem cell identity and mediates ileum-colon conversion via enhancer remodeling
Organisms
Homo sapiens
;
Mus musculus
Experiment type
Genome binding/occupancy profiling by high throughput sequencing
Expression profiling by high throughput sequencing
Summary
This SuperSeries is composed of the SubSeries listed below.
Overall design
Refer to individual Series
Citation(s)
34582804
Submission date
Apr 15, 2020
Last update date
Oct 07, 2021
Contact name
Wei Gu
E-mail(s)
wei.gu@beigene.com
Phone
13776921246
Organization name
Beigene
Department
Beigene Institute
Lab
Gu Lab
Street address
51 Rijing Road
City
Shanghai
State/province
Shanghai
ZIP/Postal code
200135
Country
China
Platforms (4)
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GPL19057
Illumina NextSeq 500 (Mus musculus)
GPL21103
Illumina HiSeq 4000 (Mus musculus)
GPL24247
Illumina NovaSeq 6000 (Mus musculus)
GPL24676
Illumina NovaSeq 6000 (Homo sapiens)
Samples (148)
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GSM4476733
WT Ileum rep 1 (ATAC-seq)
GSM4476734
WT Ileum rep 2 (ATAC-seq)
GSM4476735
WT Colon rep 1 (ATAC-seq)
GSM4476736
WT Colon rep 2 (ATAC-seq)
GSM4476737
KO Colon rep 1 (ATAC-seq)
GSM4476738
KO Colon rep 2 (ATAC-seq)
GSM4476757
WT Jejunum rep 1
GSM4476758
WT Ileum rep 1
GSM4476759
WT Cecum rep 1
GSM4476760
WT Colon rep 1
GSM4476761
WT Jejunum rep 2
GSM4476762
WT Ileum rep 2
GSM4476763
WT Cecum rep 2
GSM4476764
WT Colon rep 2
GSM4476765
WT Jejunum rep 3
GSM4476766
WT Ileum rep 3
GSM4476767
WT Cecum rep 3
GSM4476768
WT Colon rep 3
GSM4476769
KO Jejunum rep 1
GSM4476770
KO Ileum rep 1
GSM4476771
KO Cecum rep 1
GSM4476772
KO Colon rep 1
GSM4476773
KO Jejunum rep 2
GSM4476774
KO Ileum rep 2
GSM4476775
KO Cecum rep 2
GSM4476776
KO Colon rep 2
GSM4476777
KO Jejunum rep 3
GSM4476778
KO Ileum rep 3
GSM4476779
KO Cecum rep 3
GSM4476780
KO Colon rep 3
GSM4476781
KO Jejunum rep 4
GSM4476782
KO Ileum rep 4
GSM4476783
KO Cecum rep 4
GSM4476784
KO Colon rep 4
GSM4476785
WT Ileum (ScRNAseq)
GSM4476786
WT Colon (ScRNAseq)
GSM4476787
KO Colon (ScRNAseq)
GSM5100834
GFP_Negative_mouse_1
GSM5100835
GFP_Negative_mouse_2
GSM5100836
GFP_Negative_mouse_3
GSM5100837
GFP_Postive_mouse_1
GSM5100838
GFP_Postive_mouse_2
GSM5100839
GFP_Postive_mouse_3
GSM5100840
Mouse_Cas9_Ctrl_1
GSM5100841
Mouse_Cas9_Ctrl_2
GSM5100842
Mouse_Cas9_Ctrl_3
GSM5100843
Mouse_Cas9_FOXD2KO_1
GSM5100844
Mouse_Cas9_FOXD2KO_2
GSM5100845
Mouse_Cas9_FOXD2KO_3
GSM5100846
Mouse_Cas9_SATB2KO_1
GSM5100847
Mouse_Cas9_SATB2KO_2
GSM5100848
Mouse_Cas9_SATB2KO_3
GSM5100849
WT Ileum re-RNA-Seq rep 1
GSM5100850
WT Ileum re-RNA-Seq rep 2
GSM5100851
WT Ileum re-RNA-Seq rep 3
GSM5100852
WT Colon re-RNA-Seq rep 1
GSM5100853
WT Colon re-RNA-Seq rep 2
GSM5100854
WT Colon re-RNA-Seq rep 3
GSM5100855
KO Colon re-RNA-Seq rep 1
GSM5100856
KO Colon re-RNA-Seq rep 2
GSM5100857
KO Colon re-RNA-Seq rep 3
GSM5100858
Human_80_Cas9_Ctrl
GSM5100859
Human_83_Cas9_Ctlr
GSM5100860
Human_87_Cas9_Ctrl
GSM5100861
Human_88_Cas9_Ctrl
GSM5100862
Human_89_Cas9_Ctrl
GSM5100863
Human_80_Cas9_SATB2KO
GSM5100864
Human_83_Cas9_SATB2KO
GSM5100865
Human_87_Cas9_SATB2KO
GSM5100866
Human_88_Cas9_SATB2KO
GSM5100867
Human_89_Cas9_SATB2KO
GSM5100868
Human_duodenal_organoid_H357
GSM5100869
Human_duodenal_organoid_H389
GSM5100870
Human_duodenal_organoid_H407
GSM5100871
Human_duodenal_organoid_H424
GSM5100872
Human_colonic_organoid_H176
GSM5100873
Human_colonic_organoid_H254
GSM5100874
Human_colonic_organoid_H273
GSM5100875
Human_colonic_organoid_H275
GSM5100876
SATB2_ChIP in wild type colonic epithelium rep 1
GSM5100877
SATB2_ChIP in wild type colonic epithelium rep 2
GSM5100878
SATB2_ChIP in SATB2 KO colonic epithelium
GSM5100879
CDX2_ChIP in wild type colonic epithelium rep 1
GSM5100880
CDX2_ChIP in wild type colonic epithelium rep 2
GSM5100881
CDX2_ChIP in SATB2 KO colonic epithelium rep 1
GSM5100882
CDX2_ChIP in SATB2 KO colonic epithelium rep 2
GSM5100883
CDX2_ChIP in CDX2 KO colonic epithelium
GSM5100884
HNF4A_ChIP in wild type colonic epithelium rep 1
GSM5100885
HNF4A_ChIP in wild type colonic epithelium rep 2
GSM5100886
HNF4A_ChIP in SATB2 KO colonic epithelium rep 1
GSM5100887
HNF4A_ChIP in SATB2 KO colonic epithelium rep 2
GSM5100888
HNF4A_ChIP in HNF4A KO colonic epithelium
GSM5100889
Wild type colonic epithelium input rep 1
GSM5100890
Wild type colonic epithelium input rep 2
GSM5100891
SATB2 KO colonic epithelium input rep 1
GSM5100892
SATB2 KO colonic epithelium input rep 2
GSM5100926
H3K27Ac in WT Colon rep1
GSM5100927
H3K27Ac in WT Colon rep2
GSM5100928
H3K27Ac in SATB2KO Colon rep1
GSM5100929
H3K27Ac in SATB2KO Colon rep2
GSM5100930
H3K27Ac in WT Ileum rep1
GSM5100931
H3K27Ac in WT Ileum rep2
GSM5100932
H3K4Me1 in WT Colon rep1
GSM5100933
H3K4Me1 in WT Colon rep2
GSM5100934
H3K4Me1 in SATB2KO Colon rep1
GSM5100935
H3K4Me1 in SATB2KO Colon rep2
GSM5100936
H3K4Me1 in WT Ileum rep1
GSM5100937
H3K4Me1 in WT Ileum rep2
GSM5100938
IgG Control for WT Colon
GSM5100939
IgG Control for SATB2KO Colon
GSM5100940
IgG Control for WT Ileum
GSM5448121
EED_KO_Day7_Rep1
GSM5448122
EED_KO_Day7_Rep2
GSM5448123
EED_KO_Day7_Rep3
GSM5448124
EED_SATB2_KO_Day7_Rep1
GSM5448125
EED_SATB2_KO_Day7_Rep2
GSM5448126
EED_SATB2_KO_Day7_Rep3
GSM5448127
SATB2_KO_Day7_Rep1
GSM5448128
SATB2_KO_Day7_Rep2
GSM5448577
KO_Day0_rep1
GSM5448578
KO_Day0_rep2
GSM5448579
KO_Day1_rep1
GSM5448580
KO_Day1_rep2
GSM5448581
KO_Day2_rep1
GSM5448582
KO_Day2_rep2
GSM5448583
KO_Day4_rep1
GSM5448584
KO_Day4_rep2
GSM5448585
KO_Day6_rep1
GSM5448586
KO_Day6_rep2
GSM5448587
WT_Day2
GSM5448588
WT_Day6
GSM5448647
DTR_GFP(+)_SATB2
GSM5448648
DTR_GFP(-)_SATB2
GSM5448649
DTR_GFP(+)_IgG
GSM5448650
DTR_GFP(-)_IgG
GSM5448677
Embronic_day12_hindgut
GSM5448678
Embronic_day14_hindgut
GSM5448679
Embronic_day16_hindgut
GSM5448680
Postnatal_day1_hindgut
GSM5453656
WT Ileum Organoid rep 1
GSM5453657
WT Ileum Organoid rep 2
GSM5453658
WT Ileum Organoid rep 3
GSM5453659
KO Colon Organoid rep 1
GSM5453660
KO Colon Organoid rep 2
GSM5453661
KO Colon Organoid rep 3
GSM5453662
WT Colon Organoid rep 1
GSM5453663
WT Colon Organoid rep 2
GSM5453664
WT Colon Organoid rep 3
This SuperSeries is composed of the following SubSeries:
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GSE148690
ATAC-seq of Intestine Epithelia (Ileum and Colon) from Satb2-deficient and WT mice
GSE148692
Bulk RNA-seq of Intestine Epithelia (Jejunum, Ileum, Cecum and Colon) from Satb2-deficient and WT mice
GSE148693
scRNA-Seq of Intestine Epithelia (Ileum and Colon) from Satb2-deficient and WT mice
GSE167281
Bulk RNA-seq of 3D Cultured Intestinal Organoids (Ileum and Colon) from Satb2-deficient and WT mice
GSE167282
Bulk RNA-seq of Epitope Expressed SATB2 in Mouse Ileum Epithelium
GSE167283
Bulk RNA-seq of Mouse Colonic Organoids: SATB2 and FOXD2KO CRISPR Knockout
GSE167284
Bulk RNA-seq (>20M reads) of Intestine Epithelium (Ileum and Colon) from Satb2-deficient and WT mice
GSE167285
Bulk RNA-seq of CRISPR SATB2 Knockout Human Colonic Organoids
GSE167286
Bulk RNA-seq of Human Duodenal and Colonic Stem Cells
GSE167287
ChIP-seq of Colonic Intestine Epithelium from Satb2-deficient and WT mice
GSE167289
Enhancer Analysis (CUT&RUN) of Intestine Epithelium from Satb2-deficient and WT mice
GSE180013
Bulk RNA-seq of Colonic Epithelia from EED and EED/Satb2 Double Knockout Mice
GSE180023
Bulk RNA-seq of Early Time Course Colonic Epithelia from Satb2-deficient and WT mice
GSE180029
CUT&RUN Analysis of Satb2 Binding in Colonic Stem Cells and Differentiated Cells
GSE180037
ATAC-seq of Embronic Hindgut Epithelia from WT mice
Relations
BioProject
PRJNA625441
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MINiML
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TXT
Supplementary file
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Download
File type/resource
GSE148695_RAW.tar
2.4 Gb
(http)
(custom)
TAR (of BED, BW, MTX, TSV)
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