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| Status |
Public on Jul 01, 2020 |
| Title |
Brg1 restrains the pro-inflammatory properties of ILC3s and modulates intestinal immunity [ATAC-seq] |
| Organism |
Mus musculus |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
To determine the molecular regulation of ILC3s by Brg1, small intestinal ILC3s (Lin-Thy1highCD45low) from Brg1-deficient and control ILC3s were subjected to assay for transposase-accessible chromatin with high throughput sequencing (ATAC-seq).
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| Overall design |
Biological triplicates of 50000 ILC3s (Thy1.2highCD45low cells) sorted by flow cytometry from the small intestine of 7-9 week old Rag1-/-;Smarca4f/f or Rag1-/-;Rorc-cre;Smarca4f/f mice were subjected to ATAC-seq analysis.
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| Contributor(s) |
Qi X, Qiu J, Qin J, Qiu J |
| Citation(s) |
32612160 |
| |
| Submission date |
Apr 03, 2020 |
| Last update date |
Jul 03, 2020 |
| Contact name |
Ju Qiu |
| Organization name |
Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences
|
| Street address |
320 Yueyang Road
|
| City |
Shanghai |
| ZIP/Postal code |
200031 |
| Country |
China |
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| Platforms (1) |
| GPL24247 |
Illumina NovaSeq 6000 (Mus musculus) |
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| Samples (6)
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| Relations |
| BioProject |
PRJNA623010 |
| SRA |
SRP255196 |
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