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| Status |
Public on May 27, 2020 |
| Title |
Expression data from HeLa cell treated with Tris(1,3-dichloro-2-propyl)phosphate |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
Tris(1,3-dichloro-2-propyl)phosphate is widely used in consumer products as a flame retardant. Humans are often exposed to this compound. However, the molecular mechanisms of the compound`s adverse effects are still unclear. We address the molecular and cellular mechanisms underlying tris(1,3-dichloro-2-propyl)phosphate effects on HeLa cells.
Here RNA-Seq analysis was performed to identify distinct classes of up- or down-regulated genes and their connections to different metabolic pathways.
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| Overall design |
7 samples were analyzed. We compared samples treated by tris(1,3-dichloro-2-propyl)phosphate for 2 and 24 hr with the concentration of the compound 4 µM, 20 µM, and 100 µM (1 non-treated sample, 6 samples treated by the tris(1,3-dichloro-2-propyl)phosphate).
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| Contributor(s) |
Lee JS, Haque MM, Voitsitskyi T |
| Citation(s) |
35304560 |
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| Submission date |
Mar 26, 2020 |
| Last update date |
Apr 06, 2022 |
| Contact name |
Jun-Seok Lee |
| E-mail(s) |
junseoklee@kist.re.kr
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| Phone |
+82-2-958-5092
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| Organization name |
Korea Institute of Science and Technology (KIST)
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| Street address |
39-1 Hawolgok-dong Seungbuk-gu
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| City |
Seoul |
| ZIP/Postal code |
136-791 |
| Country |
South Korea |
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| Platforms (1) |
| GPL20301 |
Illumina HiSeq 4000 (Homo sapiens) |
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| Samples (7)
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| Relations |
| BioProject |
PRJNA615365 |
| SRA |
SRP254111 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE147560_data2.xlsx |
4.0 Mb |
(ftp)(http) |
XLSX |
SRA Run Selector |
| Raw data are available in SRA |
| Processed data are available on Series record |
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