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Series GSE147560 Query DataSets for GSE147560
Status Public on May 27, 2020
Title Expression data from HeLa cell treated with Tris(1,3-dichloro-2-propyl)phosphate
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary Tris(1,3-dichloro-2-propyl)phosphate is widely used in consumer products as a flame retardant. Humans are often exposed to this compound. However, the molecular mechanisms of the compound`s adverse effects are still unclear. We address the molecular and cellular mechanisms underlying tris(1,3-dichloro-2-propyl)phosphate effects on HeLa cells.
Here RNA-Seq analysis was performed to identify distinct classes of up- or down-regulated genes and their connections to different metabolic pathways.
 
Overall design 7 samples were analyzed. We compared samples treated by tris(1,3-dichloro-2-propyl)phosphate for 2 and 24 hr with the concentration of the compound 4 µM, 20 µM, and 100 µM (1 non-treated sample, 6 samples treated by the tris(1,3-dichloro-2-propyl)phosphate).
 
Contributor(s) Lee JS, Haque MM, Voitsitskyi T
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Submission date Mar 26, 2020
Last update date May 27, 2020
Contact name Jun-Seok Lee
E-mail(s) junseoklee@kist.re.kr
Phone +82-2-958-5092
Organization name Korea Institute of Science and Technology (KIST)
Street address 39-1 Hawolgok-dong Seungbuk-gu
City Seoul
ZIP/Postal code 136-791
Country South Korea
 
Platforms (1)
GPL20301 Illumina HiSeq 4000 (Homo sapiens)
Samples (7)
GSM4433467 HeLa cells, NT
GSM4433468 HeLa cells, TDCPP, 4uM-2hr
GSM4433469 HeLa cells, TDCPP, 20uM-2hr
Relations
BioProject PRJNA615365
SRA SRP254111

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Supplementary file Size Download File type/resource
GSE147560_data2.xlsx 4.0 Mb (ftp)(http) XLSX
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Raw data are available in SRA
Processed data are available on Series record

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