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Series GSE14756 Query DataSets for GSE14756
Status Public on Feb 10, 2009
Title Expression data from Drosophila histone methyltransferase mutants
Organism Drosophila melanogaster
Experiment type Expression profiling by array
Summary H3K9 methylation is a mark of inactive chromatin. In D.melanogaster, three enzymes (SU(VAR)3-9, EGG, and dG9A) are responsible for creating the H3K9 methyl mark. We have investigated the effects of loss of SU(VAR)3-9 and EGG on gene expression in adult heads using microarray analysis.

Keywords: Expression profiling by microarray
 
Overall design Heads from adults flies were used for RNA extraction and hybridization on Affymetrix microarrays. Four genotypes were used: yw; +/CyO, yw; egg235/CyO, yw; +/CyO; Su(var)3-906; yw; egg235/CyO; Su(var)3-906. For each genotype, three biological replicates were analyzed. For the yw; +/CyO control, an additional technical replicate (same RNA sample processed twice) is included. While source files for both technical replicates are included, only one was used for the final analysis.
 
Contributor(s) Riddle NC
Citation(s) 19189944
Submission date Feb 09, 2009
Last update date Aug 28, 2018
Contact name Nicole Christina Riddle
Organization name Washington University
Department Biology
Lab SCR Elgin
Street address 1 Brookings Dr.; CB1137
City St. Louis
State/province MO
ZIP/Postal code 63130
Country USA
 
Platforms (1)
GPL1322 [Drosophila_2] Affymetrix Drosophila Genome 2.0 Array
Samples (13)
GSM368567 yw rep1A
GSM368568 yw rep1B
GSM368569 yw rep2
Relations
BioProject PRJNA112251

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE14756_RAW.tar 26.5 Mb (http)(custom) TAR (of CEL)
Raw data provided as supplementary file
Processed data included within Sample table

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