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| Status |
Public on Nov 11, 2020 |
| Title |
RNA-sequencing of C3H/10T1/2 mesenchymal stem cells expressing H2B mutant histones |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
Purpose of study is to assess changes in gene expression profiles of mesenchymal stem cell upon expression of H2BE71K/Q, H2BE76K/Q and H2BE113K/Q
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| Overall design |
Examination of 3 independent biological replicates of C3H/10T1/2
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| Contributor(s) |
Patriotis AL, Carroll T, Allis CD |
| Citation(s) |
33649601 |
| NIH grant(s) |
| Grant ID |
Grant title |
Affiliation |
Name |
| P01 CA196539 |
Oncohistones: Role of Histone H3 Mutations in the Oncogenesis of Pediatric Cancers |
THE ROCKEFELLER UNIVERSITY |
CHARLES DAVID ALLIS |
| P01 CA196539 |
Project 3: Mechanisms of Methyltransferase Dysregulation by Oncohistones |
PRINCETON UNIVERSITY |
Tom Muir |
| R37 GM086868 |
Structure, Function and Applications of Inteins |
PRINCETON UNIVERSITY |
Tom Muir |
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| Submission date |
Mar 13, 2020 |
| Last update date |
Mar 03, 2021 |
| Contact name |
Agata Lemiesz Patriotis |
| E-mail(s) |
alemiesz@rockefeller.edu
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| Organization name |
Rockefeller University
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| Lab |
Chromatin Biology and Epigenetics
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| Street address |
1230 York ave
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| City |
New York City |
| State/province |
New York |
| ZIP/Postal code |
10065 |
| Country |
USA |
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| Platforms (1) |
| GPL19057 |
Illumina NextSeq 500 (Mus musculus) |
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| Samples (21)
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| GSM4411388 |
C3H/10T1/2 cells, H2BE71K, rep1 |
| GSM4411389 |
C3H/10T1/2 cells, H2BE71K, rep2 |
| GSM4411390 |
C3H/10T1/2 cells, H2BE71K, rep3 |
| GSM4411391 |
C3H/10T1/2 cells, H2BE71Q, rep1 |
| GSM4411392 |
C3H/10T1/2 cells, H2BE71Q, rep2 |
| GSM4411393 |
C3H/10T1/2 cells, H2BE71Q, rep3 |
| GSM4411394 |
C3H/10T1/2 cells, H2BE76K, rep1 |
| GSM4411395 |
C3H/10T1/2 cells, H2BE76K, rep2 |
| GSM4411396 |
C3H/10T1/2 cells, H2BE76K, rep3 |
| GSM4411397 |
C3H/10T1/2 cells, H2BE76Q, rep1 |
| GSM4411398 |
C3H/10T1/2 cells, H2BE76Q, rep2 |
| GSM4411399 |
C3H/10T1/2 cells, H2BE76Q, rep3 |
| GSM4411400 |
C3H/10T1/2 cells, H2BE113K, rep1 |
| GSM4411401 |
C3H/10T1/2 cells, H2BE113K, rep2 |
| GSM4411402 |
C3H/10T1/2 cells, H2BE113K, rep3 |
| GSM4411403 |
C3H/10T1/2 cells, H2BE113Q, rep1 |
| GSM4411404 |
C3H/10T1/2 cells, H2BE113Q, rep2 |
| GSM4411405 |
C3H/10T1/2 cells, H2BE113Q, rep3 |
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| Relations |
| BioProject |
PRJNA612510 |
| SRA |
SRP252753 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE146959_TPM_PerGroupTable.csv.gz |
856.0 Kb |
(ftp)(http) |
CSV |
| GSE146959_TPM_PerSampleTable.csv.gz |
1.6 Mb |
(ftp)(http) |
CSV |
SRA Run Selector |
| Raw data are available in SRA |
| Processed data are available on Series record |
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