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Series GSE146402 Query DataSets for GSE146402
Status Public on Aug 01, 2020
Title Characterization of a Castrate Resistant Prostate Cancer Xenograft Derived from a Patient of West African Ancestry
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary Here we report the establishment and characterization of a Prostate Cancer Patient Derived Explant (PCPDX) from a patient of West African ancestry with metastatic castration resistant disease. The following data represents gene expression in a series of mice carrying this PCPDX and undergoing different treatment courses. Mice were treated for 10 weeks with either Enzalutamide, Cisplatin, or Docetaxel, or appropriate vehicle controls.
 
Overall design RNA sequencing of gene expression in mice with prostate cancer after standard of care treatment
 
Contributor(s) Patierno BM, Foo W, Allen T, Somarelli JA, Ware KE, Gupta S, Wise S, Wise JP, Qin X, Zhang D, Xu L, Li Y, Chen X, Inman BA, McCall SJ, Huang J, Kittles RA, Owzar K, Gregory S, Armstrong AJ, George DJ, Patierno SR, Hsu DS, Freedman JA
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Submission date Mar 05, 2020
Last update date Aug 21, 2020
Contact name Jennifer Freedman
E-mail(s) jennifer.freedman@duke.edu
Phone 919-684-6354
Organization name Duke Cancer Institute
Street address 905 South Lasalle Street
City Durham
ZIP/Postal code 27710
Country USA
 
Platforms (1)
GPL24676 Illumina NovaSeq 6000 (Homo sapiens)
Samples (36)
GSM4384727 batch1_Cisplatin-1_S10
GSM4384728 batch1_Cisplatin-2_S11
GSM4384729 batch1_Cisplatin-3_S12
Relations
BioProject PRJNA610513
SRA SRP251671

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE146402_count_matrix_pdx_batch1run_S15excluded.csv.gz 1.1 Mb (ftp)(http) CSV
GSE146402_count_matrix_pdx_batch2run_S15excluded.csv.gz 1.1 Mb (ftp)(http) CSV
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Raw data are available in SRA
Processed data are available on Series record

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