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Series GSE146273 Query DataSets for GSE146273
Status Public on Oct 20, 2021
Title RNA-Seq during tumor cell plasticity and Platr18 overexpression/silencing
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary The study aims: 1-to identify transcripts that are regulated during breast tumor cell plasticity induced by TGF-beta or by the silencing of PCBP1 expression and 2- to analyze the function of Platr18 lincRNA in breast cancer cells transcriptome reprogramming.
Overall design NMuMG cells were treated with TGF-beta or with a PCBP1-shRNA to induce EMT. Cells over-expressing or silenced for Platr18 were also analyzed
Contributor(s) Grelet S, Fréreux C, Obellianne C, Noguchi K, Howley B, Dalton A, Howe P
Citation(s) 34810279
Submission date Mar 03, 2020
Last update date Jan 07, 2022
Contact name Simon Grelet
Organization name University of South Alabama - Mitchell Cancer Institute
Street address 1660 Spring Hill Ave - USA Drive North,
City Mobile, AL
State/province Alabama
ZIP/Postal code 36604
Country USA
Platforms (1)
GPL17021 Illumina HiSeq 2500 (Mus musculus)
Samples (20)
GSM4376561 NMuMG silenced for PCBP1 replicate 1
GSM4376562 NMuMG silenced for PCBP1 replicate 2
GSM4376563 NMuMG silenced for PCBP1 expressing scrambled shRNA replicate 1
BioProject PRJNA609944
SRA SRP251371

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Supplementary file Size Download File type/resource
GSE146273_Normalized_counts.txt.gz 3.2 Mb (ftp)(http) TXT
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Processed data are available on Series record

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