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Series GSE143782 Query DataSets for GSE143782
Status Public on Sep 08, 2020
Title Colon, rectum and rectal tumor organoids. Effects of calcitriol (active form of Vitamin D) treatment
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary We have established three-dimensional (3D) organoids from healthy colon and rectum tissue and from tumor tissue of patients with rectal cancer. Global transcriptomic analyses reveal differences in gene expression between these stem cell-derived cultures and distinct response to vitamin D.
 
Overall design 1,25(OH)2D3 and vehicle treated organoids from colon, rectum and rectal tumor tissue are RNA-sequenced
 
Contributor(s) Costales-Carrera A, Fernández-Barral A, Domínguez O, Burgos A, Barbáchano A, Muñoz A
Citation(s) 32824266
Submission date Jan 16, 2020
Last update date Sep 08, 2020
Contact name Alba Costales
E-mail(s) albacostales@gmail.com
Phone 0034647906865
Organization name IIB
Department cancer genetics
Lab 231
Street address Arturo Duperier, 4
City madrid
State/province madrid
ZIP/Postal code 28029
Country Spain
 
Platforms (1)
GPL16791 Illumina HiSeq 2500 (Homo sapiens)
Samples (36)
GSM4274529 R40CC: Patient #40 colon stem cells-Control
GSM4274530 R40CD: Patient #40 colon stem cells-VitaminD
GSM4274531 R40RC: Patient #40 rectum stem cells-Control
Relations
BioProject PRJNA601668
SRA SRP242197

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE143782_Fig2B_Recto_Tumor_vs_Healthy_control_cpm-2.xls.gz 2.7 Mb (ftp)(http) XLS
GSE143782_Interaction_Origin_Status_05_2020.xls.gz 387.1 Kb (ftp)(http) XLS
GSE143782_Rectum_Colon_RectalTumor_Calcitriol_regulation.xlsx 17.1 Mb (ftp)(http) XLSX
GSE143782_colon_vs_rectum_control_cpm.xlsx 4.0 Mb (ftp)(http) XLSX
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Raw data are available in SRA
Processed data are available on Series record
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