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| Status |
Public on Dec 26, 2020 |
| Title |
Gene expression after low dose irradiation in pluripotent stem cells developing to retinal ganglion cells |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
The effects of low dose irradiation on the gene expression on the neural cell development using human induced pluripotent stem cells (hiPS cells).
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| Overall design |
We irradiated 30 and 180 mGy of radiation on hiPS cells between day 4 and 5 of differentiation to determine alteration of genome-wide gene expressions on day 6, 10, 17 and 35 of development. Activated and inactivated canonical pathways were identified by ingenuity pathway analysis and upstream molecules, diseases and functions were predicted.
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| Contributor(s) |
Katsura M, Yoshihiro U, Nansai H, Kobayashi M, Taguchi A, Ishikawa Y, Ito T, Fukunaga H, Tozawa H, Chikaoka Y, Nakaki R, Echigo A, Kohro T, Sone H, Wada Y |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
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| Submission date |
Dec 27, 2019 |
| Last update date |
Dec 26, 2020 |
| Contact name |
Takahide Kohro |
| E-mail(s) |
kohro@lsbm.org
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| Phone |
81-3-5452-5237
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| Organization name |
LSBM, RCAST
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| Street address |
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| City |
4-6-1, Komaba, Meguroku |
| State/province |
Tokyo |
| ZIP/Postal code |
153-8904 |
| Country |
Japan |
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| Platforms (1) |
| GPL16791 |
Illumina HiSeq 2500 (Homo sapiens) |
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| Samples (14)
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| Relations |
| BioProject |
PRJNA597881 |
| SRA |
SRP238906 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE142658_fpkm_data.txt.gz |
995.2 Kb |
(ftp)(http) |
TXT |
SRA Run Selector |
| Raw data are available in SRA |
| Processed data are available on Series record |
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