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Series GSE142160 Query DataSets for GSE142160
Status Public on Jan 03, 2020
Title DNase-seq profiling of Saos-2 and U2OS cell lines
Organism Homo sapiens
Experiment type Genome binding/occupancy profiling by high throughput sequencing
Summary We performed DNase-seq on two osteosarcoma cell lines, Saos-2 and U2OS. This was done to identify regulatory regions within the genomes of these cells. We performed hotspot calling on these data using Hotspot2 ( to identify 51,556 DNaseI hypersensitive sites within Saos-2 cells and 63,388 within U2OS cells.
Overall design A single replicate of each of Saos-2 and U2OS cell lines was profiled using DNase-seq
Contributor(s) Hogan MS, Vulpescu NA, Maurano MT
Citation(s) 35147782
Submission date Dec 17, 2019
Last update date Feb 28, 2022
Contact name Matthew T Maurano
Organization name NYU School of Medicine
Department Institute for Systems Genetics
Lab Maurano
Street address 435 East 30th Street
City New York
State/province NY
ZIP/Postal code 10016
Country USA
Platforms (1)
GPL18573 Illumina NextSeq 500 (Homo sapiens)
Samples (2)
GSM4221654 Saos2_DNase-seq
GSM4221655 U2OS_DNase-seq
BioProject PRJNA596091
SRA SRP237908

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Supplementary file Size Download File type/resource
GSE142160_RAW.tar 280.3 Mb (http)(custom) TAR (of BED, BW)
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Raw data are available in SRA
Processed data provided as supplementary file

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