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Series GSE140781 Query DataSets for GSE140781
Status Public on Nov 22, 2019
Title The short time-series transcriptome profiles of a human adipose mesenchymal stem cell by electrical stimulation of enzymatic biofuel cell
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary We investigate the mRNA expression properties of hAD-MSCs by electrical stimulation using EBFC as an electrical regulator. We set up three different electrical currents, at 120±10.2, 250±11.5, and 500±16.2 nA/cm2 in hAD-MSCs. We performed transcriptome profiling to analyze the impact of EBFC-derived electrical current on gene expression using next-generation sequencing (NGS).
Among the 166 up-regulated genes, 98 genes were significantly enriched into the UniProtKB functional categories such as ribosomal protein, alternative splicing, ribonucleoprotein, and amino-acid biosynthesis. This indicate that the genes highly associated with metabolic regulation of cell growth and proliferation have been changed by electrical stimulation in the EBFCs.
Overall design mRNA profiles of wild-type human adipose-derived mesenchymal stem cells (hAD-MSCs) and hAD-MSCs under nano-scale electrical stimulation at 120±10.2, 250±11.5, and 500±16.2 nA/cm2, using Illumina HiSeq2500.
Contributor(s) Kang K, Han K, Mun S
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Submission date Nov 21, 2019
Last update date Nov 27, 2019
Contact name Jae Ho Lee
Organization name CHA University
Department Department of biomedical Science
Street address 120, Haeryong-ro
City Pocheon-si
State/province Gyeonggi-do
ZIP/Postal code 11160
Country South Korea
Platforms (1)
GPL16791 Illumina HiSeq 2500 (Homo sapiens)
Samples (4)
GSM4184954 hAD-MSC_Con
GSM4184955 hAD-MSC_C0.01_3Days
GSM4184956 hAD-MSC_C0.02_3Days
BioProject PRJNA590948
SRA SRP231149

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Supplementary file Size Download File type/resource
GSE140781_CDrefFlat_RPKM_table_Submit.txt.gz 381.3 Kb (ftp)(http) TXT
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Processed data are available on Series record

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